Product Details
| Product Name:
GAMBOGIC ACID |
CAS No.:
2752-65-0 |
| Min. Order:
1g |
Purity:
99% |
| Supply Ability:
100KG |
Release date:
2019/07/06 |
| Product::
AD68 |
| GAMBOGIC ACID Basic information |
| Product Name: |
GAMBOGIC ACID |
| Synonyms: |
BETA-GUTTIFERIN;BETA-GUTTILACTONE;GAMBOGIC ACID;GUTTATIC ACID;GUTTIC ACID;(z)-methyl-3-pentenyl)-;1,5-methano-1h,3h,11h-furo(3,4-g)pyrano(3,2-b)xanthene-1-crotonicacid,3a,4,5,;3,3,11-tetramethyl-13-(3-methyl-2-butenyl)-11-(4-7-tetrahydro-8-hydroxy-alph |
| CAS: |
2752-65-0 |
| MF: |
C38H44O8 |
| MW: |
628.75 |
| EINECS: |
|
| Product Categories: |
chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;Inhibitors |
| Mol File: |
2752-65-0.mol |
 |
| |
| GAMBOGIC ACID Chemical Properties |
| Melting point |
88.5°C |
| Boiling point |
586.06°C (rough estimate) |
| alpha |
D20 -685° (methanol) |
| density |
1.1057 (rough estimate) |
| refractive index |
1.5290 (estimate) |
| storage temp. |
Store at -20°C |
| solubility |
DMSO: ≥10mg/mL |
| color |
yellow to orange |
| InChIKey |
GEZHEQNLKAOMCA-XKZIYDEJSA-N |
| Hazard Codes |
T |
| Risk Statements |
25-36/37/38 |
| Safety Statements |
26-45 |
| RIDADR |
UN 2811 6.1 / PGIII |
| RTECS |
PB9268200 |
| |
| GAMBOGIC ACID Usage And Synthesis |
| Uses |
antiinflammatory, cytotoxic, inhibits HeLa cells in vitro; |
| Definition |
ChEBI: A natural product found in Garcinia hanburyi. |
| Biological Activity |
Natural product isolated from the Garcinia hanburyi tree. Induces apoptosis in several tumor cell lines including T47D cells. Activates caspases with an EC 50 value of 0.78-1.64 μ M and competitively inhibits antiapoptotic Bcl-2 family proteins (IC 50 values are 1.47, 1.21, 2.02, 0.66, 1.06 and 0.79 μ M for Bcl-XL, Bcl-2, Bcl-W, Bcl-B, Bfl-1 and Mcl-1 respectively). Also blocks K IR 2.1 channels (EC 50 ≤ 100 nM). |
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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