6-Bromo-4-hydroxycoumarin
| Price | $7500 |
| Package | 1Kg |
| Min. Order: | 0.100Kg |
| Supply Ability: | 500 Kg |
| Update Time: | 2024-09-06 |
Product Details
| Product Name: 6-Bromo-4-hydroxycoumarin | CAS No.: 4139-61-1 |
| Min. Order: 0.100Kg | Purity: 98 |
| Supply Ability: 500 Kg | Release date: 2024/09/06 |
| 6-Bromo-4-hydroxycoumarin |
6-Bromo-4-hydroxycoumarin, also known as BrHCC, is an organic compound that belongs to the tetronic acid family. It was first synthesized in 1891 by the reaction of ethyl nitroacetate and homophthalic acid. 6-Bromo-4-hydroxycoumarin is a valued reagent for the synthesis of 1,3-dicarbonyl compounds due to its high yields, easy workup, and stereoselectivity. The synthesis of 6-bromo-4-hydroxycoumarin begins with the condensation of ethyl nitroacetate with pyridine in presence of hydrochloric acid to produce a mixture of methylene chloride and 4-hydroxycoumarin. This mixture is then heated at reflux for 24 hours. The final product is purified by fractional distillation.
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