Product Details
| Product Name: 6-methyleneandrost-4-ene-3,17-dione | CAS No.: 19457-55-7 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: 5000kg | Release date: 2025/11/03 |
1,2-Dihydro Exemestane | High-Purity Anticancer Intermediate & API Synthesis Reagent 💊🔬
🌟 Product Overview
1,2-Dihydro Exemestane is a pharmaceutically active steroid derivative critical for synthesizing anticancer APIs, particularly aromatase inhibitors used in hormone-dependent cancer therapies12. As a key intermediate, it enables precise enzymatic modifications for oncology drug development, including breast and ovarian cancer treatments14. Its structural stability supports large-scale industrial synthesis and R&D applications35.
✅ Key Advantages
| ≥98% HPLC/GC-MS Purity | Validated via USP/EP protocols15 |
| High Reaction Efficiency | >85% yield in API synthesis12 |
| Low Toxicity Profile | Meets ICH S2(R1) safety guidelines15 |
| Long-Term Stability | 24-month shelf life under 2-8°C15 |
🧪 Applications
- Anticancer Drug Synthesis
: Core precursor for exemestane and other aromatase inhibitors.
- Pharmaceutical Research
: Reference standard for metabolic pathway studies45.
- Industrial Biocatalysis
: Substrate for enzyme-mediated steroid transformations13.
- Oncology Formulations
: Supports targeted therapies for hormone-sensitive cancers12.
📜 Quality Certifications
- GMP-Compliant Production
: ISO 9001-certified facilities15.
- Residual Solvents
: <50 ppm (ICH Q3C compliant)15.
- Multi-Method Validation
: NMR, FTIR, and LC-MS batch testing12.
📈 Market Trends
The global oncology intermediates market is projected to grow at 7.1% CAGR through 2030, fueled by rising demand for precision cancer therapies34. Aromatase inhibitors like exemestane dominate 22% of the hormone therapy sector, underscoring this intermediate’s commercial relevance12.



Company Profile Introduction
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