7-Chlorokynurenic acid NEW
| Price | $61 | $128 | $245 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-26 |
Product Details
| Product Name: 7-Chlorokynurenic acid | CAS No.: 18000-24-3 |
| Purity: 99.72% | Supply Ability: 10g |
| Release date: 2025/05/26 |
Product Introduction
Bioactivity
| Name | 7-Chlorokynurenic acid |
| Description | 7-Chlorokynurenic acid (7-chloro-4-hydroxy-2-carboxyquinoline) is an effecitve and selective antagonist of NMDA receptor with IC50 of 0.56 μM for the glycine B coagonist site. 7-Chlorokynurenic acid inhibits the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM and shows antinociceptive actions after neuraxial delivery. |
| In vivo | In male Sprague-Dawley rats, 7-Chlorokynurenic acid (10 nM) retardates the development of both the electroencephalographic and motor (17.7 daily stimulations) components of the seizure response[3]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 15 mg/mL (67.1 mM), Sonication is recommended. |
| Keywords | reuptake of glutamate | NMDA receptor | Glycine B coagonist site of NMDA receptor | Glutamate receptor | 7-Chlorokynurenic acid |
| Inhibitors Related | (-)-Aspartic acid | Mephenesin | Decanoic Acid | Halothane | Evans blue | L-Glutamine | Direct Blue 1 | L-Glutamic acid monosodium salt | Riluzole | Piracetam | O-Phospho-L-serine | Procaine hydrochloride |
| Related Compound Libraries | Marine Natural Product Library | Pain-Related Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Membrane Protein-targeted Compound Library | Natural Product Library | Inhibitor Library | Neuroprotective Compound Library | Microbial Natural Product Library | Natural Product Library for HTS | Bioactive Compounds Library Max | Human Metabolite Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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