7-Deaza-2'-deoxyguanosine Cas 86392-75-8 | China | Manufacturer

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Package	10g	50g

Product Details

Product Name: 7-Deaza-2'-deoxyguanosine	CAS No.: 86392-75-8
EC-No.: 500-100-4	Min. Order: 10g
Purity: 97%	Supply Ability: 100kg
Release date: 2025/11/06

7-Deaza-2'-deoxyguanosine is a synthetic nucleoside analog derived from deoxyguanosine (a DNA building block). Here's a concise breakdown:

Key Features:

Structural Modification:

The nitrogen atom at position 7 (N7) of the guanine base is replaced with carbon (C7).
The sugar moiety remains 2'-deoxyribose.
Functional Impact:

Disrupts Hoogsteen bonding: Lacks N7, critical for major-groove interactions (e.g., G-quadruplexes).
Maintains Watson-Crick pairing: Still pairs with cytosine (C), but with altered stability.
Enhanced stability: Resists enzymatic degradation better than natural deoxyguanosine.
Primary Applications:

DNA Sequencing: Reduces band compression artifacts in Sanger sequencing (especially in GC-rich regions).
Therapeutic Development: Serves as a precursor for antiviral/anticancer drugs (e.g., carbovir analogs).
Biochemical Probes: Studies DNA polymerase kinetics, nucleic acid structures, and enzyme mechanisms.
Fluorescent Labeling: C7 position can be modified for attachment of fluorophores.
Note: Often used alongside analogs like 7-deaza-dATP to resolve complex DNA secondary structures.

Significance:

This modification enables more accurate DNA analysis and facilitates the design of novel therapeutics targeting viral replication or cancer.

Article illustration

Company Profile Introduction

Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in distributing the products of our own company and affiliated enterprises, are the members of Hubei E-commerce Chamber. Our company has professional persons who major in chemical R&D and sicentific management, supply fine chemical products with high quality and close service, also supply custom-tailored products according to our clients' requirement. We have a positive and self-motivated management work team with a common philosophy, caring and commitment through teamwork, our team strive to achieve success in delighting our clients and ourselves. Since Wuhan Fortuna Chemical Co., Ltd founded, we continuously innovate our products and improve our service, sales network. Hence, we initiate the first sale mode on net in China, which is the retail trade of small package bring along wholesale of diversified management modes. Our products are exported widely to South Korea, Vietnam, Australia, Europe and South America, highly recommended by our clients.We insist on the management creed “Market is our compass, Quality is our life, Credit is our soul”. Clients’ trust is our forward powder, their satisfaction is our struggling goal.

Recommended supplier

Product name	Price		Suppliers	Update time
7-DEAZA-2'-DEOXYGUANOSINE	$0.00/1G	VIP1Y	Shenzhen Nexcon Pharmatechs Ltd.	2025-05-30
7-Deaza-2'-deoxyguanosine; ?2-Amino-7-(2-deoxy-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4(3H)-one	$0.00/5mg	VIP4Y	TargetMol Chemicals Inc.	2025-04-29
7-DEAZA-2'-DEOXYGUANOSINE	$0.00/1kg	VIP4Y	Henan Aochuang Chemical Co.,Ltd.	2022-09-23
7-DEAZA-2'-DEOXYGUANOSINE	$5.00/5KG	VIP8Y	Career Henan Chemical Co	2019-08-02

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Product Details

Key Features:

Significance:

Company Profile Introduction

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Recommended supplier

Wuhan Fortuna Chemical Co., Ltd