Taccalonolide B
| Price | $9.8 |
| Package | 1KG |
| Min. Order: | 1KG |
| Supply Ability: | 20 tons |
| Update Time: | 2020-02-07 |
Product Details
| Product Name: Taccalonolide B | CAS No.: 108885-69-4 |
| Min. Order: 1KG | Purity: ＞98%HPLC |
| Supply Ability: 20 tons | Release date: 2020/02/07 |
| Delivery Time:: Prompt | Storage:: Keep away from heat， sparks and flames |
| Package:: Bottle / Drum / Bag | Port:: Shanghai， Tianjin or Qingdao |
| Transportation:: By sea， express， air，railway | No. :: Jessie |
Jessie 785
Contact: jessie@coreychem.com
Welcome to contact us!
[Product Specification】
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Name
taccalonolide B
Synonym
More Synonyms
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Description
Taccalonolide B is microtubule stabilizer isolated from Tacca plantaginea, with antitumor activity. Taccalonolide B is effective in vitro against cell lines that overexpress P-glycoprotein (Pgp) and multidrug-resistance protein (MRP7). Taccalonolide B inhibits growth of SK-OV-3 cells with an IC50 of 208 nM[1][2].
Related Catalog
Research Areas >> Cancer
Signaling Pathways >> Cell Cycle/DNA Damage >> Microtubule/Tubulin
Signaling Pathways >> Cytoskeleton >> Microtubule/Tubulin
Target
microtubule[2]
References
[1]. LiangChen Zhong, et al. Steroidal bitter principles from tacca plantaginea structures of taccalonolide A and B. Tetrahedron Letters. 1987, 28(15): 1673-1675.
[2]. Risinger AL, et al. The taccalonolides: microtubule stabilizers that circumvent clinically relevant taxane resistance mechanisms. Cancer Res. 2008 Nov 1;68(21):8881-8.
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Density
1.4±0.1 g/cm3
Boiling Point
775.9±60.0 °C at 760 mmHg
Molecular Formula
C34H44O13
Molecular Weight
660.705
Flash Point
242.4±26.4 °C
Exact Mass
660.278198
PSA
195.49000
LogP
1.88
Vapour Pressure
0.0±6.0 mmHg at 25°C
Index of Refraction
1.604
Company Profile Introduction
Established in 2014,Career Henan Chemical Co. is a manufacturerspecializing in the sale of fine chemicals.
Mainly deals in the sales of:
Pharmaceutical intermediates
OLED intermediates：
Pharmaceutical intermediates;
OLED intermediates;
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