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Postion:Product Catalog >Natural Products>Iridoid derivatives>Catalpol
Catalpol
  • Catalpol
  • Catalpol

Catalpol NEW

Price $5 $0.1
Package 1KG 1000KG
Min. Order: 1KG
Supply Ability: g-kg-tons, free sample is available
Update Time: 2025-09-25
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Product Details

Product Name: Catalpol CAS No.: 2415-24-9
Min. Order: 1KG Purity: 98%
Supply Ability: g-kg-tons, free sample is available Release date: 2025/09/25
Lead time: In stock, ready for shipment Packaging: bag/bottle/drum/IBC
Delivery: By express, by air, by sea Origin: Manufacturer, advantage product
COA, MSDS: Available, contact us for details Name: Tina

 1. Materials information


Names

NameCatalpol
SynonymMore Synonyms

 Catalpol Biological Activity

DescriptionCatalpol, an iridoid glycoside, has neuroprotective, anti-inflammatory, and anti-hepatitis virus effects.IC50 Value:Target: neuroprotective, anti-inflammatory, and anti-hepatitis virus natural product.In vitro: Catalpol could be encapsulated into composite nanofibers and induce differentiation of hASCs into neural-like cells, which might offer new avenues in nerve regeneration [1].In vivo: The pharmacokinetics of catalpol in normal and doxorubicin-induced chronic kidney disease rats after oral administration of Rehmannia glutinosa extract was determined, and the extraction recoverie of catalpol was higher than 68.24% [2]. The protective effect of catalpol on renal IRI mice through suppressing phosphatidylinositol 3-kinase/protein kinase B (PI3K/Akt)-endothelial nitric oxide synthase (eNOS) and against inflammation, and the possible underlying mechanism [3].
Related Catalog
Signaling Pathways >> Others >> Others
Natural Products >> Terpenoids and Glycosides
Research Areas >> Others
References

[1]. Zhao M, et al.Comparative pharmacokinetics of catalpol and acteoside in normal and chronic kidney disease rats after oral administration of Rehmannia glutinosa extract. Biomed Chromatogr. 2015 May 29.

[2]. Guo JH, et al.Potential Neurogenesis of Human Adipose-Derived Stem Cells on Electrospun Catalpol-Loaded Composite Nanofibrous Scaffolds. Ann Biomed Eng. 2015 Mar 31.

[3]. Zhu J,Catalpol protects mice against renal ischemia/reperfusion injury via suppressing PI3K/Akt-eNOS signaling and inflammation. Int J Clin Exp Med. 2015 Feb 15;8(2):2038-44.

[4]. Xu Z, et al.Mitochondrial fusion/fission process involved in the improvement of catalpol on high glucose-induced hepatic mitochondrial dysfunction. Acta Biochim Biophys Sin (Shanghai). 2015 Jul 2.

 Chemical & Physical Properties

Density1.7±0.1 g/cm3
Boiling Point675.6±55.0 °C at 760 mmHg
Melting Point203-205ºC
Molecular FormulaC15H22O10
Molecular Weight362.329
Flash Point362.4±31.5 °C
Exact Mass362.121307
PSA161.60000
LogP-4.15
Vapour Pressure0.0±4.7 mmHg at 25°C
Index of Refraction1.679
Storage condition?20°C

 MSDS

Catalpol MSDS(Chinese)

 Toxicological Information

CHEMICAL IDENTIFICATION

  • RTECS NUMBER :

  • LZ5776816

  • CHEMICAL NAME :

  • beta-D-Glucopyranoside, 1a,1b,2,5a,6,6a-hexahydro-6-hydroxy- 1a-(hydroxymethyl)oxireno(4,5)cyclopenta(1,2-c)pyran- 2-yl, (1aS-(1a-alpha,1b-beta,2-beta,5a- beta,6-beta,6a-alpha))-

  • CAS REGISTRY NUMBER :

  • 2415-24-9

  • LAST UPDATED :

  • 199806

  • DATA ITEMS CITED :

  • 2

  • MOLECULAR FORMULA :

  • C15-H22-O10

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

  • TYPE OF TEST :

  • LD - Lethal dose

  • ROUTE OF EXPOSURE :

  • Oral

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • >10 gm/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • REFERENCE :

  • NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 64,93,1968

  • TYPE OF TEST :

  • LD - Lethal dose

  • ROUTE OF EXPOSURE :

  • Intravenous

  • SPECIES OBSERVED :

  • Rodent - mouse

  • DOSE/DURATION :

  • >2500 mg/kg

  • TOXIC EFFECTS :

  • Details of toxic effects not reported other than lethal dose value

  • REFERENCE :

  • NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 64,93,1968

 Safety Information

Hazard CodesXi: Irritant;
Risk PhrasesR36/37/38
Safety PhrasesS26
RIDADRNONH for all modes of transport
RTECSLZ5776816

 Synthetic Route

Previous 1/2 Next
Article illustration

rehmannioside B

CAS#:81720-06-1

~%

Article illustration

Catalpol

CAS#:2415-24-9

Literature: Oshio,H.; Inouye,H. Phytochemistry (Elsevier), 1982 , vol. 21, p. 133
Article illustration

2',3',4',6,6',1...

CAS#:6910-20-9

~%

Article illustration

(8S)-(-)-7,8-Di...

CAS#:81892-75-3

Article illustration

Catalpol

CAS#:2415-24-9

Literature: Phytochemistry (Elsevier), , vol. 21, p. 231
Article illustration

2',3',4',6',10-...

CAS#:75598-56-0

~%

Article illustration

Vanillic acid

CAS#:121-34-6

Article illustration

Catalpol

CAS#:2415-24-9

Literature: Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 43, # 5 p. 1023 - 1025

 Precursor & DownStream

Precursor  4


  • Article illustration CAS#:81720-06-1
    rehmannioside B

  • Article illustration CAS#:6910-20-9
    2',3',4',6,6',1...

  • Article illustration CAS#:75598-56-0
    2',3',4',6',10-...

  • Article illustration CAS#:1374308-81-2
    [(1aS,1bS,2S,5a...



2. Packaging of materials

  • For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.

  • For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product. 

                             Or smaller package 1kg/bottle, 10kgs/bottle as request. 


Article illustrationArticle illustration


3. Shipping & Delivery

  • By Express

Provide door to door service

Suitable for goods under 50kg

Delivery: 3-7 days

Cost: low cost

Article illustration


  • By Air

Provide airport to airport service

Suitable for goods over 50kg

Delivery: 3-14 days

Cost: high cost

Article illustration


  • By Sea

Provide seaport to seaport service

Suitable for goods over 100kg

Delivery: 2-45 days

Cost: low cost

Article illustration


4. Contact information

For more details, pls contact us freely.

Email address: Tina@fdachem.com

Mob: 86 15225627621

WhatsApp/Skype/Wechat/LINE: 86 15225627621










Company Profile Introduction

Henan Fengda Chemical Co., Ltd. is located in the High-tech Development Zone of Henan Province. Specializing in the production and sales of various fine chemical products required for industrial production, including chemical raw materials, organic raw materials, petrochemicals, chemical reagents, solvents, catalysts, and additives, etc.

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