Pyoluteorin NEW
| Price | $197 | $497 | $693 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-07-16 |
Product Details
| Product Name: Pyoluteorin | CAS No.: 25683-07-2 |
| Purity: 99.93% | Supply Ability: 10g |
| Release date: 2026/07/16 |
Product Introduction
Bioactivity
| Name | Pyoluteorin |
| Description | Pyoluteorin is an antibiotic that inhibits Oomycete fungi, including the plant pathogen Pythium ultimum, and suppresses related plant diseases. Additionally, Pyoluteorin induces apoptosis in human triple-negative breast cancer (MDA-MB-231) cells in vitro. |
| In vitro | Pyoluteorin, an antifungal compound composed of a bichlorinated pyrrole linked to a resorcinol moiety, was identified within a 24-kb genomic region of Pseudomonas fluorescens Pf-5[1]. It exhibits significant cytotoxicity towards MCF-7 cells (IC50=1.84 μM) and selective cytotoxicity against BT474, HCC1954, MAD-MB-468, MDA-MB-231, and MCF-10A cells with IC50 values of 9.75±0.16, 0.94±0.01, 3.89±0.08, 0.97±0.01, and 57.01±0.76 μM, respectively[2]. Treatment with Pyoluteorin (0.1-10 μM; for 24 hours) induces changes in apoptosis-related protein expressions and promotes cell apoptosis in MDA-MB-231 cells via Bcl-2 family proteins and caspase cascade, additionally causing cell cycle arrest in these human triple-negative breast cancer cells[2]. |
| Storage | Store under nitrogen, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 10 mg/mL (36.75 mM), Solution. DMSO : 125 mg/mL (459.42 mM), Sonication is recommended. |
| Keywords | Pyoluteorin | Antibiotic |
| Inhibitors Related | Neomycin sulfate | Calcium Propionate | Stavudine | Aceglutamide | Kanamycin sulfate | Sulfamethoxazole sodium | Terbinafine hydrochloride | Benzyl propionate | Metronidazole | Doxycycline | Formamide | Alginic acid |
| Related Compound Libraries | Anti-Tumor Natural Product Library | Apoptosis Compound Library | Polyphenolic Natural Product Library | Bioactive Compound Library | Anti-Fungal Compound Library | Antibiotics Library | Microbial Natural Product Library | Natural Product Library for HTS | Anti-infective Natural Product Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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VIP2Y
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Shaanxi Dideu New Materials Co. Ltd
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2026-06-30 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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