Product Details
| Product Name: Sildenafil citrate | CAS No.: 171599-83-0 |
| Min. Order: 1kg | Purity: 99% |
| Supply Ability: 1T | Release date: 2025/10/27 |
Sildenafil Citrate | GMP-Certified API for ED Treatment & Pulmonary Hypertension | USP Grade 💊❤️
📌 Product Overview
Sildenafil Citrate is a selective phosphodiesterase type 5 (PDE5) inhibitor primarily used to treat erectile dysfunction (ED) and pulmonary arterial hypertension (PAH)12. By enhancing nitric oxide-mediated vasodilation, it improves blood flow to target tissues, offering rapid relief (onset: 30–60 minutes) and sustained efficacy (duration: 4–6 hours)23. Widely utilized in pharmaceutical formulations and clinical research, it is compatible with oral tablets, compounded medications, and PAH-specific therapies24.
✅ Key Advantages
| ≥99% HPLC Purity | USP/EP-compliant with validated stability24 |
| High Bioavailability | Rapid absorption (Cmax: 560 ng/mL at 1 hour)23 |
| Broad Therapeutic Use | Dual applications in ED and PAH management25 |
| Cost-Effective Synthesis | Scalable production under GMP guidelines24 |
🌍 Applications
- Pharmaceuticals
: Oral tablets (25mg/50mg/100mg) for ED and PAH23.
- Research
: PDE5 inhibition studies and cardiovascular drug development25.
- Compounding Pharmacies
: Customized dosage forms for niche patient needs24.
- Veterinary Medicine
: Off-label use in animal cardiovascular research25.
📜 Quality Certifications
- GMP/ISO 9001
: Production aligns with WHO and ICH guidelines24.
- USP/EP Compliance
: Rigorous testing via HPLC, GC-MS, and dissolution profiling24.
- Residual Solvents
: <50 ppm (ICH Q3C standards)24.
📈 Market Trends
The global ED drug market is projected to reach $4.2B by 2027, driven by aging populations and lifestyle factors25. PAH therapies, including Sildenafil-based formulations, are growing at 6.8% CAGR, reflecting unmet clinical needs25.


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