Product Details
| Product Name:
Abaperidone |
CAS No.:
183849-43-6 |
| Purity:
99.77% |
Supply Ability:
10g |
| Release date:
2026/08/30 |
Product Introduction
Bioactivity
| Name | Abaperidone |
| Description | Abaperidone is a potent 5-HT2A receptor and dopamine D2 receptor antagonist with an IC50 of 6.2 for 5-HT2A receptors and 17 nM for dopamine D2 receptors.Abaperidone is a potentially atypical anti-psychotropic compound that reduces basal hsp70 mRNA expression in rat striatum and prefrontal cortex. expression in the striatum and prefrontal cortex of rats. |
| In vitro | Abaperidone exhibits a strong binding affinity for dopamine D2 receptors, as well as a higher affinity for 5-HT2 receptors, with IC50 values of 17 and 6.2 nM, respectively.[1] |
| In vivo | After oral administration of either 0.5 mg/kg of Abaperidone or risperidone, the time course of the inhibition of climbing behavior for a period of several hours is tested in mice.[1]
In a study of serum prolactin levels after oral administration of Abaperidone and haloperidol, the prolactin levels of risperidone at 5 mg/kg for either 1 or 3 days in rats, showing the prolactin levels increased in smaller than those for reference drugs. A lesser induction of catalepsy is observed for Abaperidone.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 1.46 mg/mL (3.23 mM), Sonication is recommended.
|
| Keywords | DopamineReceptor | Dopamine Receptor | D2 Receptor | Abaperidone | 5HTReceptor | 5-HT2A Receptor | 5-HT2A | 5HT Receptor |
| Inhibitors Related | Alverine citrate | Dapoxetine hydrochloride | Cefaclor monohydrate | Hexamethonium Bromide | Octopamine hydrochloride | 1,8-Cineole | L-DOPA | Creatine | Oxolinic acid | Mianserin hydrochloride | Trazodone hydrochloride | Cinchonidine |
| Related Compound Libraries | Bioactive Compounds Library Max | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Anti-Alzheimer's Disease Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Bioactive Compound Library | Neurotransmitter Receptor Compound Library | Angiogenesis related Compound Library | Inhibitor Library | GPCR Compound Library | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$168.00
|
VIP5Y
|
TargetMol Chemicals Inc.
|
2026-07-14 |
United States