Product Details
| Product Name: Ademetionine 1,4-butanedisulfonate | CAS No.: 101020-79-5 |
| Min. Order: 1KG | Purity: 98% |
| Supply Ability: g-kg-tons, free sample is available | Release date: 2025/09/25 |
| Lead time: In stock, ready for shipment | Packaging: bag/bottle/drum/IBC |
| Delivery: By express, by air, by sea | Origin: Manufacturer, advantage product |
| COA, MSDS: Available, contact us for details | Name: Tina |
1. Materials information
| Name | Ademetionine 1,4-butanedisulfonate |
|---|---|
| Synonym | More Synonyms |
| Description | SAMe-1,4-Butanedisulfonate, a natural compound, is a methyl donor in the central nervous system. SAMe-1,4-Butanedisulfonate has antidepressant activity. SAMe-1,4-Butanedisulfonate can be used for research of CNS disorders[1][2][3][4]. |
|---|---|
| Related Catalog | Research Areas >> Inflammation/Immunology Research Areas >> Neurological Disease |
| In Viv | Animal Model: Mice submitted to the forced swimming test (FST) and tail suspension test (TST)[4] Dosage: 10, 255, 50, 100, 200 mg/kg Administration: i.p. Result: Reduced the immobility time in the FST and reduced the total distance traveled. |
| References | [1]. Delle Chiaie R, et al. Efficacy and tolerability of oral and intramuscular S-adenosyl-L-methionine 1,4-butanedisulfonate (SAMe) in the treatment of major depression: comparison with imipramine in 2 multicenter studies. Am J Clin Nutr. 2002 Nov;76(5):1172S-6S. [2]. Barceló HA, et al. Osteoartritis experimental y su evolución bajo tratamiento con S-adenosil-L-metionina (SAMe) [Experimental osteoarthritis and its course when treated with S-adenosyl-L-methionine]. Rev Clin Esp. 1990 Jun;187(2):74-8. Spanish. [3]. Stramentinoli G, et al. Protective role of S-adenosyl-L-methionine on liver injury induced by D-galactosamine in rats. Biochem Pharmacol. 1978 May 15;27(10):1431-3. [4]. Sales AJ, et al. S-adenosyl-l-methionine antidepressant-like effects involve activation of 5-HT1A receptors. Neurochem Int. 2023 Jan;162:105442. |
| Melting Point | 125-135°C |
|---|---|
| Molecular Formula | C42H74N12O28S8 |
| Molecular Weight | 1451.621 |
| Exact Mass | 1450.250122 |
| PSA | 798.02000 |
| LogP | 3.14480 |
| Hazard Codes | Xi |
|---|
2. Packaging of materials
For powders: normal is 25kgs/Drum or bag, or larger/smaller package as request.
For liquids: normal 25kgs/drum, 180-300kgs/bucket, or IBC, determined by the nature of the product.
Or smaller package 1kg/bottle, 10kgs/bottle as request.
3. Shipping & Delivery
By Express
Provide door to door service
Suitable for goods under 50kg
Delivery: 3-7 days
Cost: low cost
By Air
Provide airport to airport service
Suitable for goods over 50kg
Delivery: 3-14 days
Cost: high cost
By Sea
Provide seaport to seaport service
Suitable for goods over 100kg
Delivery: 2-45 days
Cost: low cost
4. Contact information
For more details, pls contact us freely.
Email address: Tina@fdachem.com
Mob: 86 15225627621
WhatsApp/Skype/Wechat/LINE: 86 15225627621
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