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Postion:Product Catalog >API>Veterinary raw materials>Afoxolaner
Afoxolaner
  • Afoxolaner
  • Afoxolaner
  • Afoxolaner
  • Afoxolaner
  • Afoxolaner

Afoxolaner NEW

Price $1
Package 1kg
Min. Order: 1kg
Supply Ability: 10000
Update Time: 2025-10-13

Product Details

Product Name: Afoxolaner CAS No.: 1093861-60-9
Min. Order: 1kg Purity: 99%
Supply Ability: 10000 Release date: 2025/10/13

Article illustration

Afoxolaner (CAS 1093861-60-9) – Chemical Properties & Overview

Property Description

IUPAC Name:4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]-N-[2-oxo-2-(2,2,2-trifluoroethylamino)ethyl]-1-naphthalenecarboxamide

Molecular Formula:C₂₆H₁₄ClF₆N₃O₃

Molecular Weight:553.85 g/mol

CAS Number:1093861-60-9

Appearance:White to pale yellow crystalline powder

Solubility:Insoluble in water; soluble in DMSO, ethanol

Melting Point:150–155°C

Chemical Class:Isoxazoline derivative

Mechanism of Action:GABA/glutamate-gated chloride channel inhibitor (arthropod-specific)

Primary Use:Veterinary ectoparasiticide (fleas & ticks)

Target Animals:Dogs (oral administration)

Commercial Products:NexGard® (Merial/Boehringer Ingelheim)

Regulatory Approvals:FDA (USA), EMA (EU), VICH guidelines

Key Benefits:Monthly oral treatment, rapid killing of parasites, low mammalian toxicity

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Afoxolaner (CAS 1093861-60-9) - Quality Control Specification

ParameterSpecificationTest Method
AppearanceWhite to pale yellow crystalline powderVisual inspection
IdentificationComplies (HPLC/IR vs. reference standard)HPLC, IR spectroscopy
Purity (HPLC)≥ 98.0%Reverse-phase HPLC
Water Content (KF)≤ 0.5% w/wKarl Fischer titration
Residue on Ignition≤ 0.1%USP <281>
Heavy Metals≤ 10 ppm (as Pb)ICP-MS / USP <231>
Related SubstancesTotal impurities ≤ 2.0%
Any single impurity ≤ 0.5%
HPLC (area normalization)
Particle Size90% ≤ 100 µm (customizable)Laser diffraction (if applicable)
SolubilityInsoluble in water;
Soluble in DMSO/ethanol
Solubility test
Microbial LimitsTotal aerobic count ≤ 1000 CFU/g
Yeast/mold ≤ 100 CFU/g
No pathogens detected
USP <61>, <62>
Storage Conditions2-8°C (dry, protected from light)Label requirement
Shelf Life24 months (unopened, under recommended storage)Stability studies

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Company Profile Introduction

Wuhan Hao Rong Biotechnology Co., Ltd., located in East Lake high tech Development Zone, Wuhan, is a company specializing in the production and operation of chemical raw materials, flavors and fragrances, food additives, agrochemicals and other products. The company has first-class production equipment, advanced production technology, scientific management system, perfect detection means, and an excellent R & D team. The R & D center of the company has a technical team specialized in research and development, as well as a number of advanced detection, experiment and pilot equipment, and has established a good technical support relationship with a number of scientific research institutions, with strong technical force. The company has a wide range of products, in line with the quality of survival, service and development, customer-centric, integrity management philosophy, do our best to provide customers with quality and cheap raw materials. In addition, haorong also helps customers develop and implement customized system solutions. In these core areas of the chemical industry, haorong's core expertise covers chemicals and application technology, flexible asset management and customized services.

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