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Postion:Product Catalog >Biochemical Engineering>Inhibitors>Endocrinology & Hormones>Androgen Receptor agonists>Andarine
Andarine
  • Andarine
  • Andarine
  • Andarine

Andarine

Price $10
Package 1kg
Min. Order: 1kg
Supply Ability: Ex 20 tons
Update Time: 2022-09-27

Product Details

Product Name: Andarine CAS No.: 401900-40-1
EC-No.: 206-141-6 Min. Order: 1kg
Purity: 99% Supply Ability: Ex 20 tons
Release date: 2022/09/27

Andarine Biological Activity

DescriptionAndarine (S-4) is an investigational selective androgen receptor modulator (SARM) and an active partial agonist.
Related Catalog
Signaling Pathways >> Others >> Androgen Receptor
Research Areas >> Cancer
Solvent
In Vitro:

DMSO : ≥ 100 mg/mL (226.57 mM)

* "≥" means soluble, but saturation unknown.

In Vivo: 1.Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline) Solubility: ≥ 2.5 mg/mL (5.66 mM); Clear solution 2.Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline Solubility: ≥ 2.5 mg/mL (5.66 mM); Clear solution
Solubility1 mM2.2657 mL11.3286 mL22.6572 mL5 mM0.4531 mL2.2657 mL4.5314 mL10 mM0.2266 mL1.1329 mL2.2657 mL
StoragePowder-20°C3 years 4°C2 yearsIn solvent-80°C6 months -20°C1 month
ShippingRoom temperature in continental US; may vary elsewhere
SMILESO=C([C@@](O)(COC1=CC=C(C=C1)NC(C)=O)C)NC2=CC=C(C(C(F)(F)F)=C2)[N+]([O-])=O
References

[1]. Thevis M, Geyer H, Kamber M, Sch?nzer W.Detection of the arylpropionamide-derived selective androgen receptor modulator (SARM) S-4 (Andarine) in a black-market product.Drug Test Anal. 2009 Aug;1(8):387-92.

[2]. Thevis M, Thomas A, Fussh?ller G, Beuck S, Geyer H, Sch?nzer W.Mass spectrometric characterization of urinary metabolites of the selective androgen receptor modulator andarine (S-4) for routine doping control purposes.Rapid Commun Mass Spectrom. 2010 Aug

[3]. Thomas A, Geyer H, Sch?nzer W, Crone C, Kellmann M, Moehring T, Thevis M.Sensitive determination of prohibited drugs in dried blood spots (DBS) for doping controls by means of a benchtop quadrupole/Orbitrap mass spectrometer.Anal Bioanal Chem. 2012 May;40

[4]. Guddat S, Solymos E, Orlovius A, Thomas A, Sigmund G, Geyer H, Thevis M, Sch?nzer W.High-throughput screening for various classes of doping agents using a new 'dilute-and-shoot' liquid chromatography-tandem mass spectrometry multi-target approach.Drug Tes

[5]. Chen J, Kim J, Dalton JT. Discovery and therapeutic promise of selective androgen receptor modulators. Mol Interv. 2005 Jun;5(3):173-88.

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 Chemical & Physical Properties

Density1.5±0.1 g/cm3
Boiling Point698.7±55.0 °C at 760 mmHg
Melting Point70-74ºC
Molecular FormulaC19H18F3N3O6
Molecular Weight441.358
Flash Point376.4±31.5 °C
Exact Mass441.114777
PSA133.48000
LogP4.01
Vapour Pressure0.0±2.3 mmHg at 25°C
Index of Refraction1.605
Storage conditionRefrigerator

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