Product Details
| Product Name: ARG-GLY-ASP | CAS No.: 99896-85-2 |
| Min. Order: 1KG | Purity: 99% |
| Supply Ability: 1T | Release date: 2025/10/22 |
| Product Name: | ARG-GLY-ASP |
| Synonyms: | H2N-RGD-OH;H-ARG-GLY-ASP-OH;L-ARG-GLY-ASP;ARGINYL-GLYCYL-ASPARTIC ACID;ARG-GLY-ASP;ARG-GLY-ASP PEPTIDE;Arg-Gly-Asp acetate;Arginyl-glycyl-asparagilin |
| CAS: | 99896-85-2 |
| MF: | C12H22N6O6 |
| MW: | 346.34 |
| EINECS: | |
| Product Categories: | Peptide;Cell Signaling Enzymes;ECM ProteinsCytoskeleton and Extracellular Matrix;Extracellular Matrix;Extracellular Matrix Peptides (ECM);Extracellular Matrix Peptides and ProteinsPeptides for Cell Biology;Fibronectin Fragments and Analogs;Matrix Metalloproteinases Products;Various Peptides |
| Mol File: | 99896-85-2.mol |
 | |
| ARG-GLY-ASP Chemical Properties |
| Melting point | 153-155℃ (ethyl ether ) |
| density | 1.61±0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | Soluble in 0.1N acetic acid at 20mg/ml |
| pka | 2.85±0.10(Predicted) |
| form | Powder |
| color | White to off-white |
| biological source | synthetic |
| Water Solubility | Soluble to 12 mg/mL (34.64 mM) in Water |
| Sequence | Arg-Gly-Asp |
| InChIKey | IYMAXBFPHPZYIK-BQBZGAKWSA-N |
| SMILES | C(O)(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)N |
| Safety Information |
| WGK Germany | 3 |
| MSDS Information |
| Provider | Language |
|---|---|
| SigmaAldrich | English |
| ARG-GLY-ASP Usage And Synthesis |
| Chemical Properties | White to off-white powder |
| Uses | Arg-Gly-Asp has been used:
|
| Definition | ChEBI: Arg-Gly-Asp is an oligopeptide. |
| General Description | Arg-Gly-Asp (RGD) is an integrin binding site, which belongs to the class of adhesive proteins. It functions as a brain tumor targeting ligand. |
| Biological Activity | synthetic peptides containing the arginine-glycine-aspartate (rgd) were extensively used as inhibitors of integrin-ligand interactions in studies of cell adhesion, migration, growth and differentiation, since the rgd motif is an integrin-recognition motif found in many ligands. |
| Biochem/physiol Actions | Primary sequence involved with the binding of proteins to cell surfaces |
| in vitro | rgd peptide can induce apoptosis in the absence of signals and integrin-mediated cell clustering. previous study demonstrates that rgd peptides promote apoptosis through activation of conformation changes enhancing pro-caspase-3 activation and autoprocessing [1]. |
| in vivo | anima study suggested that the rgd-4c-fitc-peptide bound to both endothelial and tumor cells in vivo and that peptide targeting should allow the delivery of therapeutic drugs to both endothelial and tumor cells [2]. |
| target | integrin-ligand interaction |
| storage | Store at -20°C |
| references | [1] nature. 1999 feb 11;397(6719):534-9.rgd peptides induce apoptosis by direct caspase-3 activation. buckley cd1, pilling d, henriquez nv, parsonage g, threlfall k, scheel-toellner d, simmons dl, akbar an, lord jm, salmon m. [2] cancer res. 2002 sep 15;62(18):5139-43. arginine-glycine-aspartic acid (rgd)-peptide binds to both tumor and tumor-endothelial cells in vivo. zitzmann s1, ehemann v, schwab m. |
Company Profile Introduction
Shandong Hanjiang Chemical Co., Ltd. is located in Zibo City, Shandong Province, China.
It is a biotechnology enterprise engaged in the R&D, production and sales of drugs, steroids, peptides, raw materials, vitamins, food additives, animal and plant extracts, cosmetics, pharmaceutical raw materials and intermediates. The company has complete experimental facilities. Advanced testing instruments ensure the stability of product quality from all aspects. The company has a complete sales service system, and its products are exported to countries all over the world. It has won a good international reputation for its excellent quality and excellent service. The company has been adhering to the basic principles of "integrity, quality, service, and win-win" to serve customers, and constantly strict requirements,
Advantages:
1. Samples are provided for test;
2. Good quality products;
3. 100% secure delivery.
4. secure your money, lower the risk
Payment ways: Western Union, Moneygram, Bitcoin, T/T
Delivery: EMS/ EUB/ USPS/ UPS/ TNT/ FEDEX/ DHL etc
Packaging:safe and discreet packaging
Our company Superiority
1 Best service, high quality and reasonable price
2. It's customers' right to choose the package (EMS, DHL, FedEx, UPS);
3. It's customers' right to choose the packing way for his products from many recent effective packing ways
4. Specials are possible when client's order is big enough, including the discount policy;
5.Our company promise to deliver clients' package to his hands safely, or we'll cover the total loss and reship in time;
Our company supply high quality chemical products with the most competitive prices.
If have any need or question, contact us freely.
Hope we can have chances to build good long-term cooperation.
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