Azathioprine NEW
| Price | $45 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-23 |
Product Details
| Product Name: Azathioprine | CAS No.: 446-86-6 |
| Purity: 99.90% | Supply Ability: 10g |
| Release date: 2025/10/23 |
Product Introduction
Bioactivity
| Name | Azathioprine |
| Description | Azathioprine (BW 57-322), an immunosuppressive agent, inhibits purine synthesis and GTP-binding protein Rac1 activation. |
| In vitro | In murine and rat brain allografts, the combination of Azathioprine with Cyclosporin A or Prednisolone significantly enhances survival rates. |
| In vivo | Azathioprine inhibits Rac1 target genes in primary human CD4+ T lymphocytes, leading to apoptosis via the mitochondrial pathway. In isolated rat hepatocytes, Azathioprine depletes reduced glutathione (GSH), releases lactate dehydrogenase, and decreases cellular viability. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (180.34 mM), Sonication is recommended. |
| Keywords | Rheumatic diseases | Rac1 | Inhibitor | inhibit | Infectious skin diseases | HGPRT | Azathioprine | Autoimmunity inhibitor | Apoptosis | 6-Mercaptopurine |
| Inhibitors Related | Stavudine | 5-Fluorouracil | Flubendazole | Cysteamine hydrochloride | Myricetin | Sodium 4-phenylbutyrate | L-Ascorbic acid | L-Glutamic acid | Tributyrin | L-Ascorbic acid sodium salt | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
| Related Compound Libraries | Bioactive Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Anti-Cancer Clinical Compound Library | Anti-Viral Compound Library | Drug Repurposing Compound Library | Anti-Cancer Approved Drug Library | FDA-Approved Drug Library | Bitter Compound library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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