Baicalin NEW
| Price | $31 | $44 | $53 |
| Package | 50mg | 100mg | 500mg |
| Supply Ability: | 10g |
| Update Time: | 2026-08-20 |
Product Details
| Product Name: Baicalin | CAS No.: 21967-41-9 |
| Purity: 99.32% | Supply Ability: 10g |
| Release date: 2026/08/20 |
Product Introduction
Bioactivity
| Name | Baicalin |
| Description | Baicalin (Baicalein 7-O-β-D-glucuronide) is a prolyl endopeptidase inhibitor isolated from Scutellaria baicalensis that exhibits anti-inflammatory, antioxidant, antitumor, and antiviral activity. Baicalin can be used in research on inflammation, neurodegenerative diseases, tumors, and metabolic syndrome. |
| In vitro | Methods: RAW264.7 cells were treated with baicalin (12.5, 25, 50 μM) for 24 hours. Surface CD14 and TLR4 proteins were detected by flow cytometry, and CD14 mRNA was detected by RT-qPCR. Results: Baicalin dose-dependently inhibited CD14 protein and mRNA expression without affecting TLR4 expression. [1] |
| In vivo | Methods: C57BL/6 mice were established with ulcerative colitis (UC) by free access to a 3% DSS solution for 5 days. Following modeling, Baicalin (100 mg/kg) was administered orally via gavage once daily for 5 consecutive days. Results: Baicalin treatment restored colon length, reduced spleen index, alleviated ulcer severity, and significantly suppressed CD14 and IL-6 expression in colonic mucosa. [1] Methods: Adult male SD rats received continuous oral administration of Baicalin (20, 60, 120 mg/kg) once daily for two weeks prior to surgery. Following drug administration, the left anterior descending artery (LAD) was ligated for 45 minutes, followed by reperfusion for 180 minutes to establish an MI/RI model. Results: I/R significantly impaired cardiac function. Baicalin at 60 and 120 mg/kg significantly improved HR, LVSP, LVFS, and LVEF in a dose-dependent manner. [2] |
| Storage | Keep away from direct sunlight,Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 37 mg/mL (82.89 mM), Sonication is recommended. Ethanol : < 1 mg/mL (insoluble or slightly soluble) 10% DMSO+90% Saline : 10 mg/mL (22.4 mM), Solution. H2O : < 1 mg/mL (insoluble or slightly soluble) 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (8.96 mM), Sonication is recommended. |
| Keywords | Nuclear factor-κB | Nuclear factor-kappaB | NF-κB | NFκB | NF-kB | NFkB | Inhibitor | inhibit | Human immunodeficiency virus | HIVProtease | HIV Protease | HIV | GABAReceptor | GABAR | GABA Receptor | Baicalin | Baicalein 7-O-beta-D-glucuronide | Baicalein 7-O-b-D-glucuronide | Autophagy |
| Inhibitors Related | Stavudine | Aceglutamide | Hemin | Emtricitabine | Guanidine hydrochloride | Hydroxychloroquine | Lamivudine | Ethyl linoleate | D-Psicose | Paeonol | Alginic acid | Dextran sulfate sodium salt (MW 5000) |
| Related Compound Libraries | Polyphenolic Natural Product Library | Flavonoid Natural Product Library | Anti-Neurodegenerative Disease Compound Library | Pain-Related Compound Library | Traditional Chinese Medicine Monomer Library | Bioactive Compound Library | Natural Product Library | Natural Product Library for HTS | Anti-virus Traditional Chinese Medicine Monomer Library | Ion Channel Targeted Library | Ancient Chinese Classical Formulas Compound Library | Anti-Cancer Drug Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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