BMS-654457 NEW
| Price | $1970 | $2580 | $3400 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: BMS-654457 | CAS No.: 1004551-41-0 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | BMS-654457 |
| Description | BMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa) with inhibition constants (Kis) of 0.2 nM for human FXIa and 0.42 nM for rabbit FXIa. |
| In vitro | BMS-654457 demonstrates comparable in vitro potency against FXIa and exhibits over 500-fold selectivity against coagulation-related proteases [thrombin, FXa, and FVIIa] across these species. |
| In vivo | BMS-654457 is potent in the prevention of arterial thrombosis in rabbits with limited effects on bleeding time. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | BMS654457 | BMS-654457 | BMS 654457 |
| Inhibitors Related | Edoxaban | Zifaxaban | Heparin sodium salt | Edoxaban Tosylate Monohydrate | Gabexate mesylate | BISMUTH SUBGALLATE | Letaxaban | Apixaban | 2-Methoxyphenothiazine | 4-Chlorophenylurea | Fidexaban | Coumarin |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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United States