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Postion:Product Catalog >BMS-654457
BMS-654457
  • BMS-654457

BMS-654457 NEW

Price $1970 $2580 $3400
Package 25mg 50mg 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-10-27

Product Details

Product Name: BMS-654457 CAS No.: 1004551-41-0
Supply Ability: 10g Release date: 2025/10/27

Product Introduction

Bioactivity

NameBMS-654457
DescriptionBMS-654457 is a small-molecule, reversible inhibitor of factor XIa (FXIa) with inhibition constants (Kis) of 0.2 nM for human FXIa and 0.42 nM for rabbit FXIa.
In vitroBMS-654457 demonstrates comparable in vitro potency against FXIa and exhibits over 500-fold selectivity against coagulation-related proteases [thrombin, FXa, and FVIIa] across these species.
In vivoBMS-654457 is potent in the prevention of arterial thrombosis in rabbits with limited effects on bleeding time.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
KeywordsBMS654457 | BMS-654457 | BMS 654457
Inhibitors RelatedEdoxaban | Zifaxaban | Heparin sodium salt | Edoxaban Tosylate Monohydrate | Gabexate mesylate | BISMUTH SUBGALLATE | Letaxaban | Apixaban | 2-Methoxyphenothiazine | 4-Chlorophenylurea | Fidexaban | Coumarin

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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TargetMol Chemicals Inc.

4YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, USA
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