BMS-986121 NEW
| Price | Get Latest Price |
| Package | 1removed |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-17 |
Product Details
| Product Name: BMS-986121 | CAS No.: 313671-26-0 |
| Supply Ability: 10g | Release date: 2025/09/17 |
Product Introduction
Bioactivity
| Name | BMS-986121 |
| Description | BMS-986121 is a selective positive allosteric modulator (PAM) of the μ opioid receptor with analgesic effects. |
| In vitro | Method: In CHO-μ cells, BMS-986121 (1 μM–1 mM) was used to evaluate its effect on low-concentration endomorphin-I-induced β-arrestin recruitment and the enhancement of forskolin-stimulated adenylyl cyclase inhibition. At a concentration of 100 μM, its impact on the potency of endomorphin-I and leu-enkephalin in inhibiting cAMP accumulation was measured. Results: BMS-986121 significantly enhanced the β-arrestin recruitment and inhibitory effects of endomorphin-I. At 100 μM, BMS-986121 increased the potency of endomorphin-I and leu-enkephalin by approximately 4-fold and 6-fold, respectively.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 80 mg/mL (218.45 mM), Sonication is recommended. |
| Keywords | BMS-986121 | BMS 986121 |
| Inhibitors Related | Docusate sodium | Bevenopran | Mirtazapine | (-)-Menthol | SCH 221510 | Naltrexone hydrochloride | Cebranopadol | Loperamide hydrochloride | Trimebutine | Mianserin hydrochloride | Amentoflavone | Trimebutine maleate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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