Bupivacaine hydrochloride NEW
| Price | $35 | $39 | $53 |
| Package | 100mg | 200mg | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-28 |
Product Details
| Product Name: Bupivacaine hydrochloride | CAS No.: 18010-40-7 |
| Purity: 100% | Supply Ability: 10g |
| Release date: 2025/04/28 |
Product Introduction
Bioactivity
| Name | Bupivacaine hydrochloride |
| Description | Bupivacaine hydrochloride (Vivacaine) is a long-acting, amide-type local anesthetic. Bupivacaine hydrochloride reversibly binds to specific sodium ion channels in the neuronal membrane, resulting in a decrease in the voltage-dependent membrane permeability to sodium ions and membrane stabilization; inhibition of depolarization and nerve impulse conduction; and a reversible loss of sensation. |
| In vitro | Bupivacaine can induce calcium release from the sarcoplasmic reticulum (SR) in rats and suppress the SR's uptake of calcium. |
| In vivo | In vitro, Bupivacaine exhibits cytotoxic effects on bovine articular chondrocytes after an exposure of 15 to 30 minutes. It acts on isolated mitochondria as an uncoupler of oxygen consumption and adenosine diphosphate phosphorylation. Concentration-dependent mitochondrial depolarization and pyridine nucleotide oxidation are induced by Bupivacaine in these isolated mitochondria. Additionally, Bupivacaine triggers the opening of the permeability transition pore (PTP), a cyclosporin A-sensitive inner membrane channel pivotal in various forms of cell death. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 16.67 mg/mL (51.31 mM), Sonication is recommended. H2O : 21 mg/mL (64.64 mM), Sonication is recommended. Ethanol : 60 mg/mL (184.68 mM), Sonication is recommended. |
| Keywords | SodiumChannel | Sodium Channel | Potassium Channel | pain | NMDA | Na+ channels | Na channels | local | KcsA | Ionotropic glutamate receptors | Inhibitor | inhibit | iGluR | electrophysiology | channel | Calcium Channel | Ca2+ channels | Ca channels | Bupivacaine hydrochloride | Bupivacaine Hydrochloride | Bupivacaine | anesthetics |
| Inhibitors Related | Phenytoin sodium | Procaine | Lidocaine Hydrochloride hydrate | Lidocaine | Safinamide | Valproic Acid | Lidocaine hydrochloride | L-Aspartic aicd sodium | Mebeverine hydrochloride | Amitriptyline hydrochloride | Riluzole | Benzocaine |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Membrane Protein-targeted Compound Library | EMA Approved Drug Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Neuroprotective Compound Library | FDA-Approved Drug Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | Ion Channel Targeted Library | Anti-Cancer Drug Library |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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