C75 NEW
| Price | $41 | $59 | $98 |
| Package | 1mg | 2mg | 5mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2026-04-10 |
Product Details
| Product Name: C75 | CAS No.: 218137-86-1 |
| Purity: 98.84% | Supply Ability: 10g |
| Release date: 2026/04/10 |
Product Introduction
Bioactivity
| Name | C75 |
| Description | C75 is an inhibitor synthetic fatty-acid synthase (FASN) and inhibits prostate cancer cells PC3 (IC50: 35 μM).C75 increases CPT1 activity and reduces DIO. |
| In vitro | C75 (10-50 μM) reduces the growth of LNCaP spheroids in a concentration-dependent manner (IC50: 50 μM). (-)-C75 inhibits FAS activity and has a cytotoxic effect on tumor cell lines, without affecting food consumption. (+)-C75 inhibits CPT1 and produces anorexia. The differential activity of C75 enantiomers may lead to the development of potential new specific drugs for cancer and obesity [2]. |
| In vivo | C75 (i.p.) blocks fasting-induced c-Fos expression in the arcuate nucleus, lateral hypothalamic area, and paraventricular nucleus. C75 (30 mg/kg, i.p.) inhibits the food intake of mice by ≥95% within 2 h[3]. C75-treated DIO mice have a 50% greater weight loss, and a 32.9% increased production of energy because of fatty acid oxidation. C75 treatment of rodent adipocytes and hepatocytes and human breast cancer cells increases fatty acid oxidation and ATP levels by increasing CPT-1 activity, even in the presence of elevated concentrations of malonyl-CoA [4]. |
| Storage | Store at low temperature | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 0.5% CMC-Na : 5 mg/mL (19.66 mM), Suspension. DMSO : 75.6 mg/mL (297.26 mM), Sonication is recommended. |
| Keywords | PC3 cell | FattyAcidSynthase | Fatty Acid Synthase (FASN) | Fatty Acid Synthase | C75 | C 75 |
| Inhibitors Related | 2-Octanone | Betulin | Malic enzyme inhibitor ME1 | Maltitol | Coenzyme A | Pyrazinamide | A-769662 | trans-Chalcone | Orlistat | L-Carnitine | Pseudoprotodioscin | Lycorine |
| Related Compound Libraries | Bioactive Compound Library | Anti-Obesity Compound Library | Anti-Viral Compound Library | Inhibitor Library | Anti-Prostate Cancer Compound Library | Lipid Metabolism Compound Library | Metabolism Compound Library | Bioactive Compounds Library Max | Anti-Infection Compound Library | Anti-Cancer Compound Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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$929.00 / 100μg
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Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $41.00/1mg |
VIP6Y
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TargetMol Chemicals Inc.
|
2026-04-10 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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