CCPA NEW
| Price | $42 | $98 | $156 |
| Package | 1mg | 5mg | 10mg |
| Supply Ability: | 10g |
| Update Time: | 2026-08-20 |
Product Details
| Product Name: CCPA | CAS No.: 37739-05-2 |
| Purity: 99.91% | Supply Ability: 10g |
| Release date: 2026/08/20 |
Product Introduction
Bioactivity
| Name | CCPA |
| Description | CcpA (Catabolite Control Protein A) is a global transcriptional regulator in Gram-positive bacteria that governs carbon catabolite repression and metabolic flux. It directly binds to catabolite-responsive elements (cre) in target promoters, such as the ackA and pta genes, modulating their expression in response to carbohydrate availability and environmental pH. Research applications include investigating how CcpA coordinates virulence factor expression, biofilm formation (e.g., through synergistic control with CidR of the cidABC operon), and bacterial stress tolerance, including sensitivity to antimicrobial fatty acids. Deletion of ccpA alters infectivity in hyperglycemic hosts and rebalances bacterial growth versus host tissue damage in pathogenesis models. |
| In vitro | CCPA suppressed the mRNA and protein expressions of CnAβ and exerted antihypertrophic effects to a greater degree than CsA. The inhibition of CCPA on cardiomyocyte hypertrophy was counteracted by the A1 receptor antagonist DPCPX[1]. |
| In vivo | CCPA (CCPA) was synthesized as a potential high affinity ligand for A1 adenosine receptors. Binding of [3H]PIA to A1 receptors of rat brain membranes was inhibited by CCPA with a Ki-value of 0.4 nM, compared to a Ki-value of 0.8 nM for the parent compound N6-cyclopentyladenosine (CPA)[2]. |
| Storage | Keep away from direct sunlight, Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | 10% DMSO+90% Saline : 10 mg/mL (27.04 mM), Solution. DMSO : 235 mg/mL (635.48 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.41 mM), Sonication is recommended. |
| Keywords | AdenosineReceptor | Adenosine Receptor | A1 | 2-Chloro-N-6-cyclopentyladenosine | 2ChloroN6cyclopentyladenosine | 2 Chloro N6 cyclopentyladenosine |
| Inhibitors Related | Stavudine | Aceglutamide | Urea | Tamoxifen | Cysteamine hydrochloride | Metronidazole | Citric Acid Triammonium | Formamide | Dimethyl phthalate | Alginic acid | Sodium Molybdate | Sildenafil citrate |
| Related Compound Libraries | Bioactive Compounds Library Max | DNA Damage & Repair Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | ReFRAME Related Library | Bioactive Compound Library | Neurotransmitter Receptor Compound Library | NO PAINS Compound Library | GPCR Compound Library | Anti-Cancer Compound Library | Human Metabolite Library | Nucleotide Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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