Product Details
| Product Name:
CMP8 |
CAS No.:
851107-28-3 |
| Purity:
99.38% |
Supply Ability:
10g |
| Release date:
2026/01/04 |
Product Introduction
Bioactivity
| Name | CMP8 |
| Description | CMP8 is a selective ligand for estrogen receptor. CMP8 binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 has IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, respectively. |
| In vivo | CMP8 is dosed in male Balb-c mice (4 mg/kg, ip). In mammalian cells, the plasma concentration after 4 h is 1.5-fold its EC50. It has a Cmax of 0.5 μM after 30 min.[1][2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (94.68 mM), Sonication is recommended.
|
| Keywords | progestogenReceptor | progestogen Receptor | MGRERα | MGERα | Inhibitor | inhibit | hERβ | hERα | EstrogenReceptor | Estrogen Receptor/ERR | Estrogen Receptor | ERR | CMP-8 | CMP8 | CMP 8 |
| Inhibitors Related | Tamoxifen | Mifepristone | Estradiol | Astragaloside IV | Progesterone | Bisphenol B | Mequinol | Phthalic acid | Ethisterone | Alpha-Estradiol | Ferrous Bisglycinate | Cholesterol |
| Related Compound Libraries | Nuclear Receptor Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Anti-Ovarian Cancer Compound Library | Multi-Target Compound Library | NO PAINS Compound Library | Endocrinology-Hormone Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$1.00/1KG |
VIP7Y
|
Career Henan Chemical Co
|
2020-02-05 |
United States