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Postion:Product Catalog >Chemical Reagents>Organic reagents>Acyl halide>Dabsyl chloride
Dabsyl chloride
  • Dabsyl chloride

Dabsyl chloride NEW

Price $38
Package 100mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-09-30

Product Details

Product Name: Dabsyl chloride CAS No.: 56512-49-3
Purity: ≥98% Supply Ability: 10g
Release date: 2025/09/30

Product Introduction

Bioactivity

NameDabsyl chloride
DescriptionDabsyl chloride (DABS-Cl) is an amine derivatizing agent and able to give rise to stable products that can be easily monitored spectrophotometrically at 460 nm.
In vitroInstructions I. Solution preparation 1. Mother solution preparation: Dabsyl chloride is usually dissolved in organic solvents such as dimethyl sulfoxide (DMSO) or acetone. If it is needed for a specific reaction, it can also be dissolved in water. 2. Working solution preparation: Dilute the mother solution into the working solution when using it, adjust it according to the specific experimental conditions, and set a concentration gradient if necessary. II. Operation steps 1. Labeling reaction: Dabsyl chloride is labeled with free amine groups (such as amino acids or proteins) through nucleophilic substitution reactions. The amine groups of the target molecules react with Dabsyl chloride to form stable dabsyl products. 3. Reaction conditions: Buffer: The reaction is usually carried out in a weakly alkaline solution with a pH value generally between 8.5 and 9.5. Temperature: The reaction is carried out at room temperature. If the reaction needs to be accelerated, the temperature can be appropriately increased. Reaction time: The reaction time varies depending on the concentration of the amine group and Dabsyl chloride, usually 30 minutes to 1 hour. 4. Product detection: The generated dabsylation product usually has a characteristic absorption peak at 460 nm in a UV-Vis spectrophotometer, which can be used to quantitatively detect the labeling efficiency. 5. Purification: After the reaction, unreacted Dabsyl chloride and free amine groups can be removed by dialysis, gel filtration or chromatography, depending on the size of the labeled molecule.
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 3.24 mg/mL (10.01 mM), Sonication is recommended.
KeywordsInhibitor | inhibit | Dabsyl Chloride | Dabsyl chloride | Dabsyl
Related Compound LibrariesHuman Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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