Fluorescein isothiocyanate NEW

Fluorescein isothiocyanate

Modify Date: 2024-01-02 06:13:12

Fluorescein isothiocyanate structure	Common Name	Fluorescein isothiocyanate
	CAS Number	3326-32-7	Molecular Weight	389.381
	Density	1.5±0.1 g/cm3	Boiling Point	708.6±60.0 °C at 760 mmHg
	Molecular Formula	C21H11NO5S	Melting Point	>360 °C(lit.)
	MSDS	ChineseUSA	Flash Point	382.4±32.9 °C
	Symbol	GHS08	Signal Word	Danger

Purity		Quantity		Budget		Inquiry

Use of Fluorescein isothiocyanate FITC is a derivative of fluorescein for the labeling of amines.

• Properties

• Articles2410

• Spectrum

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 Names

Name	fluorescein 5-isothiocyanate
Synonym	More Synonyms

 Fluorescein isothiocyanate Biological Activity

Description	FITC is a derivative of fluorescein for the labeling of amines.
Related Catalog	Signaling Pathways >> Others >> Others Dye Reagents Research Areas >> Others
In Vitro	Annexin V-FITC/PI is employed to detect chondrocyte apoptosis[1]. The PEI-modified CDs are conjugated with fluorescein isothiocyanate (FITC) to fabricate CDs-FITC composites[2].
Cell Assay	The frequency of chondrocyte apoptosis is measured by flow cytometry with Annexin V-fluorescein isothiocyanate (FITC) and propidium iodide. A total of 1×104 treated chondrocytes are collected from each group, washed in cold PBS and incubated with Annexin V-FITC and PI at room temperature for 15 min in the dark on ice. These samples are then analyzed using a fluorescence-activated cell sorter. Cell Quest software is used to analyze the percentage of apoptosis. All tests are repeated in triplicate.
References	[1]. Gao SG, et al. Phosphorylation of osteopontin has proapoptotic and proinflammatory effects on human knee osteoarthritis chondrocytes. Exp Ther Med. 2016 Nov;12(5):3488-3494. Epub 2016 Oct 5. [2]. Zhu X, et al. Ratiometric, visual, dual-signal fluorescent sensing and imaging of pH/copper ions in real samples based on carbon dots-fluorescein isothiocyanate composites. Talanta. 2017 Jan 1;162:65-71

 Chemical & Physical Properties

Density	1.5±0.1 g/cm3
Boiling Point	708.6±60.0 °C at 760 mmHg
Melting Point	>360 °C(lit.)
Molecular Formula	C21H11NO5S
Molecular Weight	389.381
Flash Point	382.4±32.9 °C
Exact Mass	389.035797
PSA	120.44000
LogP	4.00
Vapour Pressure	0.0±2.3 mmHg at 25°C
Index of Refraction	1.754
Storage condition	2-8°C
Stability	Stability Stable, but moisture-sensitive. Incompatible with strong oxidizing agents, strong bases, amines, acids.
Water Solubility	practically insoluble

 MSDS

Fluorescein isothiocyanate MSDS(Chinese)

 Safety Information

Symbol	GHS08
Signal Word	Danger
Hazard Statements	H317-H334
Precautionary Statements	P261-P280-P342 + P311
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R22;R36/37/38;R42/43
Safety Phrases	S22-S45-S36/37/39-S26-S36/37
RIDADR	NONH for all modes of transport
WGK Germany	3

Company Profile

     Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. 

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Our Company

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Based on industry norms, customer requirements, and internal quality objectives, we establish clear quality standards. By monitoring the production process in real-time, we ensure that every step conforms to the predetermined quality standards.

Excellent quality is one of the cornerstones of our success. We welcome ordering samples for quality testing.

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Our technological innovation is reflected in the development of new materials that are at the leading edge of the industry. These materials not only possess higher performance and lower costs but also enable sustainable use within an environmentally friendly production process.

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