Galidesivir triphosphate NEW
| Price | Get Latest Price |
| Package | 25mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-08-21 |
Product Details
| Product Name: Galidesivir triphosphate | CAS No.: 1467740-78-8 |
| Supply Ability: 10g | Release date: 2025/08/21 |
Product Introduction
Bioactivity
| Name | Galidesivir triphosphate |
| Description | Galidesivir triphosphate is a substrate for viral RNA-dependent RNA polymerase (RDRP), resulting in termination of viral RNA replication and thus serves as an antiviral. Galidesivir triphosphate inhibits HCV NS5B RNA polymerase activity and protects mice against Ebola. Galidesivir triphosphate (Immucillin-A triphosphate) is converted by the prodrug Galidesivir. |
| In vitro | Galidesivir is converted to the mono-, di-, and triphosphates in virus-infected human Huh-7 cells.?Galidesivir triphosphate (Immucillin-A triphosphate) (1-60 μM) inhibits hepatitis C virus (HCV) RNA polymerase transcriptional activity in a cell-free, isolated enzyme transcription assay.The triphosphate is a substrate for viral RNA-dependent RNA polymerase.?Its incorporation permits the addition of a few additional encoded bases at which point the Galidesivir-modified RNA cannot be elongated.In virus-infected cells, Galidesivir is converted to the triphosphate, is incorporated into the viral transcript, and functions as an atypical chain-terminator for RNA-dependent RNA polymerases. |
| In vivo | In vivo conversion of Galidesivir to its TP (Galidesivir triphosphate) nucleotide is particularly efficient. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Immucillin-A Triphosphate | Immucillin-A | Galidesivir triphosphate | Galidesivir Triphosphate | Galidesivir | BCX-6870 | BCX 6870 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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