Galidesivir NEW
| Price | $163 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-11 |
Product Details
| Product Name: Galidesivir | CAS No.: 249503-25-1 |
| Purity: 99.13% | Supply Ability: 10g |
| Release date: 2025/10/11 |
Product Introduction
Bioactivity
| Name | Galidesivir |
| Description | Galidesivir (BCX4430) is a broad-spectrum antiviral compound, an adenosine analog that inhibits viral RNA-dependent RNA polymerase (RdRp) activity.Galidesivir inhibits a wide range of RNA viral pathogens in vitro, and reduces lung infections in infected animals. |
| In vitro | Galidesivir (BCX4430) undergoes phosphorylation by cellular kinases to form a triphosphate that mimics ATP. The monophosphate nucleotide of the drug is then incorporated by viral RNA polymerases into the growing RNA chain, leading to premature chain termination[1].In inhibiting the infection of Vero cells with Yellow Fever Virus (YFV), Galidesivir demonstrates effectiveness. The EC50, as determined by the neutral red uptake assay, is 8.3 μg/ml (24.5 μM)[4]. |
| In vivo | Galidesivir (BCX4430) exhibits activity following intramuscular, intraperitoneal, and oral administration in various experimental infections. In nonclinical studies involving lethal infections with Ebola virus, Marburg virus, Rift Valley fever virus, and Yellow Fever virus, Galidesivir has demonstrated pronounced efficacy[1].In a hamster model of Yellow Fever (YF), Galidesivir administered at 4 mg/kg via intraperitoneal injection twice daily for 7 days proves to be effective[3]. |
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 50 mg/mL (188.49 mM), Sonication is recommended. |
| Keywords | RNASynthesis | RNA Synthesis | RNA polymerase | RdRp | Galidesivir | DNASynthesis | DNA Synthesis | BCX-4430 | BCX 4430 | Antiviral |
| Inhibitors Related | 5-Fluorouracil | Phenytoin sodium | Adenine hemisulfate | Hydroxychloroquine | Guanidine hydrochloride | Methotrexate disodium | L-Lysine | Adenine | Sodium formate | Ofloxacin | Carbazole | Thymidine |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | Drug Repurposing Compound Library | Anti-Viral Compound Library | Bioactive Compounds Library Max | Cell Cycle Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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TargetMol Chemicals Inc.
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| $163.00/1mg |
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TargetMol Chemicals Inc.
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2025-10-11 |
United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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