Gastric Juice Peptide Fragment trifluoroacetate salt

Price	$10
Package	1kg

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Product Name: Gastric Juice Peptide Fragment trifluoroacetate salt	CAS No.: 137525-51-0
Min. Order: 1kg	Purity: 99%
Supply Ability: Ex 20 tons	Release date: 2022/10/14

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Use of Gastric Juice Peptide Fragment trifluoroacetate salt

BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis[1][2].

Name	Bpc 15
Synonym	More Synonyms

Description	BPC 157 is a stable gastric pentadecapeptide and a partial sequence of the human gastric juice protein BPC. BPC 157 is an anti-ulcer peptidergic agent with no reported toxicity. BPC 157 links inflammatory bowel disease and multiple sclerosis[1][2].
Related Catalog	Research Areas >> Inflammation/Immunology
Target	Human Endogenous Metabolite
In Vivo	BPC 157 successfully heals the intestinal anastomosis, gastrocutaneous, duodenocutaneous and colocutaneous fistulas in rats, as well as interacting with the NO-system[1]. BPC 157 (10 μg/kg, 10 ng/kg) is applied either intraperitoneally once time daily (first application immediately after surgery, last at 24 hours before sacrifice) or per-orally in drinking water (0.16 μg/ml/12 ml/day till the sacrifice). A multiple sclerosis suited toxic rat model, cuprizone (compared with standard, a several times higher regimen, 2.5% of diet regimen + 1 g/kg intragastrically/day) was combined with BPC 157 (in drinking water 0.16 μg or 0.16 ng/ml/12 ml/day/rat + 10 μg or 10 ng/kg intragastrically/day) till the sacrifice at day 4. In general, the controls could not heal cysteamine colitis and colon-colon anastomosis. BPC 157 induced an efficient healing of both at the same time[2].
Solvent	In Vitro: DMSO : 100 mg/mL (70.45 mM; Need ultrasonic) In Vivo: 1. Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% saline Solubility: ≥ 2.5 mg/mL (1.76 mM); Clear solution 2. Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in saline) Solubility: ≥ 2.5 mg/mL (1.76 mM); Clear solution 3. Add each solvent one by one: 10% DMSO 90% corn oil Solubility: ≥ 2.5 mg/mL (1.76 mM); Clear solution
Solubility	1 mM0.7045 mL3.5223 mL7.0445 mL5 mM0.1409 mL0.7045 mL1.4089 mL10 mM0.0704 mL0.3522 mL0.7045 mL
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Shipping	Room temperature
References	[1]. Sikiric P, et al. Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract. Curr Pharm Des. 2011;17(16):1612-1632. [2]. Klicek R, et al. Stable gastric pentadecapeptide BPC 157 heals cysteamine-colitis and colon-colon-anastomosis and counteracts cuprizone brain injuries and motor disability. J Physiol Pharmacol. 2013;64(5):597-612.

Density	1.4±0.1 g/cm3
Boiling Point	1802.9±65.0 °C at 760 mmHg
Molecular Formula	C62H98N16O22
Molecular Weight	1419.536
Flash Point	1044.2±34.3 °C
Exact Mass	1418.704102
LogP	-2.41
Vapour Pressure	0.0±0.6 mmHg at 25°C
Index of Refraction	1.576

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Use of Gastric Juice Peptide Fragment trifluoroacetate salt

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Min. Order:	1kg
Supply Ability:	Ex 20 tons
Update Time:	2022-10-14