I-OMe-Tyrphostin AG 538 NEW
| Price | $51 | $122 | $197 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-19 |
Product Details
| Product Name: I-OMe-Tyrphostin AG 538 | CAS No.: 1094048-77-7 |
| Purity: 98.23% | Supply Ability: 10g |
| Release date: 2025/09/19 |
Product Introduction
Bioactivity
| Name | I-OMe-Tyrphostin AG 538 |
| Description | I-OMe-Tyrphostin AG 538 is a specific IGF-1R inhibitor and ATP-competitive inhibitor of PI5P4Kα (IC50: 1 µM).I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and exhibits preferential cytotoxicity to nutrient-deficient PANC1 cells. |
| In vitro | I-OMe Tyrhost AG 538 (0-3 µM; 1 hour) can prevent the phosphorylation of Akt, IGF-1R, and Erk.[1] I-OMe Tyrphostin AG 538 (0.1-1000 µM; 24 hours) has cytotoxicity on PANC-1 cells in nutrient deficient culture medium.[1] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 50 mg/mL (114.37 mM), Sonication is recommended. |
| Keywords | PI5P4Kα | I-OMe-Tyrphostin AG-538 | I-OMe-Tyrphostin AG538 | I-OMe-Tyrphostin AG 538 | I-OMe-AG-538 | I-OMe-AG538 | IGF-1R | IGF1R |
| Inhibitors Related | Myricetin | Erucic acid | Indirubin Derivative E804 | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | 3-Methyladenine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | Inavolisib | Quercetin Dihydrate | Apilimod |
| Related Compound Libraries | Glycometabolism Compound Library | Bioactive Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Autophagy Compound Library | Angiogenesis related Compound Library | Inhibitor Library | Metabolism Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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