Product Details
| Product Name:
KP136 |
CAS No.:
76239-32-2 |
| Purity:
98.61% |
Supply Ability:
10g |
| Release date:
2025/11/03 |
Product Introduction
Bioactivity
| Name | KP136 |
| Description | KP136 (AL136) is an orally active anti-allergic compound that inhibits histamine release and is used in studies of asthma and allergic edema. |
| In vitro | KP136 (0.01 μg/mL) inhibits histamine release and degranulation in a dose-dependent manner, confirming its role as an inhibitor of mast cell activation[1]. |
| In vivo | KP136 (1 mg/kg, i.v.) also significantly inhibited 5-hour homologous PCA with activity similar to that of C4C. 0.2 mg/kg of C4C produced comparable effects to 1 mg/kg of KP136 or 5 mg/kg of DSCG. However, C4C is less effective orally, as it only produces about 35% maximal inhibition even at a high dose of 100 mg/kg, whereas KP136 produces about 66% significant inhibition at an oral dose of 2 mg/kg [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | KP-136 | KP136 | KP 136 | HistamineReceptor | Histamine release | Histamine Receptor | AL-136 | AL 136 |
| Inhibitors Related | Chlorphenesin | Histamine dihydrochloride | Meclizine dihydrochloride | Mirtazapine | Lidocaine | Famotidine | Mebhydrolin napadisylate | Sodium butanoate | Amitriptyline hydrochloride | Alginic acid | Trazodone hydrochloride | Mianserin hydrochloride |
| Related Compound Libraries | Histamine & Melatonin Receptor-Targeted Compound Library | Pain-Related Compound Library | Bioactive Compound Library | Neuronal Signaling Compound Library | Membrane Protein-targeted Compound Library | Neurotransmitter Receptor Compound Library | Orally Active Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
-
CAS:128427-86-1
$190.00 / 1mg
-
CAS:86780-90-7
$38.00 / 10mg
-
CAS:509-18-2
$47.00 / 5mg
Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$/ |
|
Anhui Ruihan Technology Co., Ltd
|
2023-08-21 |
United States