LAZABEMIDE NEW
| Price | $50 | $108 | $182 |
| Package | 10mg | 25mg | 50mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2026-05-11 |
Product Details
| Product Name: LAZABEMIDE | CAS No.: 103878-84-8 |
| Supply Ability: 10g | Release date: 2026/05/11 |
Product Introduction
Bioactivity
| Name | LAZABEMIDE |
| Description | Lazabemide (Ro 19-6327) is a selective and reversible monoamine oxidase B (MAO-B) inhibitor with IC50 values of 0.03 μM for MAO-B and >100 μM for MAO-A. |
| In vitro | LAZABEMIDE is selective, high-affinity ligands for enzymes.?KD and Bmax values for 3H-Ro 41 1049 in rat cerebral cortex were 10.7 nM and 7.38 pmol/mg protein, respectively, and for 3H-Ro 19 6327 were 18.4 nM and 3.45 pmol/mg protein, respectively.?In accordance with their potencies as enzyme inhibitors, binding to MAO-A and MAO-B was competitively inhibited by clorgyline (IC50 = 1.4 nM) and L-deprenyl (selegiline;?IC50 = 8.0 nM), respectively[1]. |
| In vivo | Lazabemide is a reversible inhibitor of monoamine oxidase B (MAO-B) with IC50 values of 0.48 and 1.5 μM measured in platelets of human subjects ages 19-36 and 60-78, respectively[2]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 34 mg/mL (170.31 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween-80+45% Saline : 0.5 mg/mL (2.5 mM), Sonication is recommended. |
| Keywords | smoking cessation | radical generation | parkinson | MonoamineOxidase | Monoamine Oxidase | MAO-B | MAO | LAZABEMIDE | Inhibitor | inhibit | ichemia | DOPAC | disease | alzheimer′s |
| Inhibitors Related | Safinamide | 1,4-Naphthoquinone | 4-Chlorochalcone | Paeonol | Hydroxylamine hydrochloride | Isatin | Methylene Blue trihydrate | β-Aminopropionitrile | Aminoacetone hydrochloride | Allylthiourea | D-(-)-Quinic acid | Amitraz |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States