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Postion:Product Catalog >ML367
ML367
  • ML367

ML367 NEW

Price $40 $64 $129
Package 5mg 10mg 25mg
Supply Ability: 10g
Update Time: 2026-07-27

Product Details

Product Name: ML367 CAS No.: 381168-77-0
Purity: 99.39% Supply Ability: 10g
Release date: 2026/07/27

Product Introduction

Bioactivity

NameML367
DescriptionML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and serves as a probe molecule with low micromolar inhibitory activity.
In vitroML367, a probe molecule that has low micromolar inhibitory activity in the ATAD5 destabilizer screen run with 10 μM 5-fluorouridine (5-FUrd) as the DNA damaging agent. Interestingly, ML367 was found to block general DNA damage responses including RPA32-phosphorylation and CHK1-phosphorylation in response to UV irradiation. In this regard, the probe molecule could block DNA repair pathways that function upstream of ATAD5.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information10% DMSO+90% Saline : 2.45 mg/mL (7.33 mM), Suspension.
DMSO : 24.5 mg/mL (73.28 mM), Sonication is recommended.
10% DMSO+40% PEG300+5% Tween 80+45% Saline : 4 mg/mL (11.96 mM), Sonication is recommended.
KeywordsML-367 | ML367 | ML 367 | Inhibitor | inhibit | EpigeneticReaderDomain | Epigenetic Reader Domain | ATPase family AAA domain-containing protein 5 (ATAD5)
Inhibitors RelatedABBV-744 | 3-methyl-1,2,3,4-tetrahydroquinazolin-2-one | (+)-JQ-1 | Tuvusertib | ZEN-3694 | Prexasertib | 5-Ph-IAA | Curcumin | Naphthol AS-E | Revumenib | JQ-1 (carboxylic acid) | Bisdemethoxycurcumin
Related Compound LibrariesHistone Modification Compound Library | Bioactive Compound Library | Epigenetics Compound Library | Kinase Inhibitor Library | Bioactive Compound Library Plus | Inhibitor Library | NO PAINS Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Cancer Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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6YR United StatesUnited States
  • Since: 2011-01-07
  • Address: 36 Washington Street, Wellesley Hill, MA
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