N,N'-Dimethylthiourea|T40615|TargetMol | United States | Manufacturer

Price	$129
Package	5g

Product Details

Product Name: N,N'-Dimethylthiourea	CAS No.: 534-13-4
Purity: ≥98%	Supply Ability: 10g
Release date: 2025/10/21

Product Introduction

Bioactivity

Name	N,N'-Dimethylthiourea
Description	N,N'-Dimethylthiourea (DMTU) (DMTU), isolated from Allii Sativi Bulbus, is an orally active scavenger of hydroxyl radical ( OH) and blocks OH production by activated neutrophils in vitro. N,N'-Dimethylthiourea protects against water-immersion restraint stress (WIRS)-induced gastric mucosal lesions in rats by exerting its antioxidant action including OH scavenging and anti-inflammatory action [1][2] .
In vivo	N,N'-Dimethylthiourea (DMTU; 1, 2.5, or 5 mmol/kg; orally) administered at 0.5 h before the onset of WIRS reduces the severity of gastric mucosal lesions with attenuation of the changes in the levels of gastric mucosal MPO, pro-inflammatory cytokines, LPO, NOx, nonprotein SH, and vitamin C and gastric adherent mucus found at 3 h after the onset of WIRS in a dose-dependent manner in Male Wistar rats aged 6 weeks [1]. DMTU protects against WIRS-induced gastric mucosal lesions in rats by exerting its antioxidant action including ·OH scavenging and its anti-inflammatory action without affecting the stress response.
Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Solubility Information	DMSO : 50 mg/mL (479.98 mM), Sonication is recommended.
Keywords	WIRS \| scavengin \| orally \| N,N'-Dimethylthiourea \| N,N'Dimethylthiourea \| N,N' Dimethylthiourea \| Inhibitor \| inhibit \| Antioxidant
Inhibitors Related	Ethoxyquin \| Cysteamine hydrochloride \| Acetylcysteine \| Imeglimin hydrochloride \| L-Ascorbic acid \| AFMK \| Glucosamine \| Gallic Acid Monohydrate \| L-Cystine \| Coenzyme Q10 \| L-Ascorbic acid sodium salt \| Sodium 2-oxopropanoate
Related Compound Libraries	Bioactive Compound Library \| Selected Plant-Sourced Compound Library \| Antioxidant Compound Library \| Anti-Inflammatory Traditional Chinese Medicine Compound Library \| Natural Product Library \| Natural Product Library for HTS \| RO5 Drug-like Natural Product Library \| Orally Active Compound Library \| Immunology/Inflammation Compound Library \| Anti-Aging Compound Library \| Bioactive Compounds Library Max \| Human Metabolite Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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Min. Order:
Supply Ability:	10g
Update Time:	2025-10-21

N,N'-Dimethylthiourea NEW

Product Details

Product Introduction

Bioactivity

Company Profile Introduction

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TargetMol Chemicals Inc.