PF-03463275 NEW
| Price | $51 | $122 | $197 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-09 |
Product Details
| Product Name: PF-03463275 | CAS No.: 1173239-39-8 |
| Purity: 99.86% | Supply Ability: 10g |
| Release date: 2025/11/09 |
Product Introduction
Bioactivity
| Name | PF-03463275 |
| Description | PF-03463275 is an orally active and selective reversible inhibitor of competitive glycine transporter protein-1 (GlyT1) with a Ki of 11.6 nM.PF-03463275 has CNS permeability and may be used to ameliorate cognitive deficits associated with schizophrenia. |
| In vivo | PF-03463275 (1-10 mg/kg; s.c.; Male Sprague-Dawley rats) induces a dose-dependent reduction in the amplitude of oscillatory potentials (OPs) elicited from dark-adapted rats.[2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 30 mg/mL (79.61 mM), Sonication is recommended. |
| Keywords | PF3463275 | PF-03463275 | PF03463275 | PF 3463275 | PF 03463275 | GlyT1 |
| Inhibitors Related | Sarcosine | Opiranserin hydrochloride | Tilapertin | Iclepertin | Org 25543 hydrochloride | Bitopertin (R enantiomer) | Opiranserin | LY2365109 hydrochloride | Bitopertin | ALX-1393 | Amoxapine | GlyT1 Inhibitor 1 |
| Related Compound Libraries | Failed Clinical Trials Compound Library | Bioactive Compound Library | Anti-Neurodegenerative Disease Compound Library | Neuronal Signaling Compound Library | Drug Repurposing Compound Library | Inhibitor Library | Bioactive Compounds Library Max | Fluorochemical Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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