PI3Kα/mTOR-IN-1 NEW
| Price | $656 | $1290 | $1730 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-04-27 |
Product Details
| Product Name: PI3Kα/mTOR-IN-1 | CAS No.: 1013098-90-2 |
| Purity: 99.3% | Supply Ability: 10g |
| Release date: 2025/04/27 |
Product Introduction
Bioactivity
| Name | PI3Kα/mTOR-IN-1 |
| Description | PI3Kα/mTOR-IN-1 is a potent dual inhibitor of PI3Kα/mTOR, with an IC50 of 7 nM for PI3Kα in a cell assay and Kis of 12.5 nM and 10.6 nM for mTOR and PI3Kα [in a cell-free assay], respectively. |
| In vitro | PI3Kα/mTOR-IN-1 exhibited excellent kinase selectivity from Pfizer’s in-house kinase selectivity panel of 43 kinases[1]. |
| In vivo | PI3Kα/mTOR-IN-1 exhibited exhibited moderate clearance, moderate Vdss, T1/2 of 0.9 h, and good oral bioavailability[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : 11 mg/mL (35.44 mM), Sonication is recommended. |
| Keywords | PI3Kα/mTOR-IN-1 | PI-3Kα/mTOR-IN-1 | PI3Kα/mTORIN1 | PI3Kα/mTOR IN 1 | PI3Kα | PI3Kalpha/mTOR-IN-1 | PI3Ka/mTOR-IN-1 | mTOR |
| Inhibitors Related | L-Leucine | Myricetin | Erucic acid | Sapanisertib | (2S,3R,4S)-4-Hydroxyisoleucine | 3-Methyladenine | Duvelisib (R enantiomer) hydrochloride | Isoprenaline hydrochloride | Quercetin | Quercetin Dihydrate | Apilimod | Rapamycin |
| Related Compound Libraries | PI3K-AKT-mTOR Compound Library | Bioactive Compound Library | HIF-1 Signaling Pathway Compound Library | Kinase Inhibitor Library | Anti-Ovarian Cancer Compound Library | Autophagy Compound Library | Inhibitor Library | Metabolism Compound Library | Anti-Aging Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | Anti-Liver Cancer Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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