Product Details
| Product Name: Pimobendan | CAS No.: 74150-27-9 | 
| Min. Order: 1KG | Purity: 99% | 
| Supply Ability: 10000 | Release date: 2025/10/13 | 

English Name:Pimobendan
Synonyms:UD-CG 212 BS, Acardi
IUPAC Name:4,5-Dihydro-6-[2-(4-methoxyphenyl)-1H-benzimidazol-5-yl]-5-methyl-3(2H)-pyridazinone
Molecular Weight:334.37 g/mol
CAS Number:74150-27-9
Appearance:White to off-white crystalline powder
Solubility:Slightly soluble in water, soluble in dimethyl sulfoxide (DMSO) and methanol
Melting Point:~260–263 °C (decomposes)
pKa:~7.4 (weakly basic)
Mechanism of Action:Phosphodiesterase III (PDE III) inhibitor with calcium-sensitizing effects, increasing myocardial contractility and vasodilation.
Therapeutic Use:Veterinary medicine: Treatment of congestive heart failure (CHF) in dogs, particularly for dilated cardiomyopathy (DCM) and mitral valve disease (MVD).

| Parameter | Specification | Test Method | Result | 
|---|---|---|---|
| Product Name | Pimobendan | - | Complies | 
| CAS No. | 74150-27-9 | - | Complies | 
| Batch No. | (e.g., PB20240701) | - | (Custom) | 
| Manufacture Date | YYYY-MM-DD | - | (Custom) | 
| Expiry Date | YYYY-MM-DD | - | (Custom) | 
| Appearance | White to off-white powder | Visual | White powder | 
| Assay (HPLC) | ≥98.5% - 101.0% | USP/EP HPLC | 99.2% | 
| Related Substances | ≤0.5% (Total impurities) | HPLC | 0.3% | 
| Water Content | ≤0.5% (Karl Fischer) | USP <921> | 0.2% | 
| Residue on Ignition | ≤0.1% | USP <281> | 0.05% | 
| Heavy Metals | ≤10 ppm (as Pb) | USP <231> / ICP-MS | <5 ppm | 
| Solubility | Slightly soluble in water | Pharmacopoeia | Complies | 
| Microbial Limits | TAMC ≤1000 CFU/g, TYMC ≤100 CFU/g | USP <61> | Complies | 
| Melting Point | 260-263°C (dec.) | USP <741> | 261°C | 
| Particle Size | 100% pass 80 mesh (Optional) | Sieve Analysis | 100% passed | 

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- Since: 2019-11-21
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