Propargyl-PEG1-acid NEW
| Price | Get Latest Price |
| Package | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-10-27 |
Product Details
| Product Name: Propargyl-PEG1-acid | CAS No.: 55683-37-9 |
| Supply Ability: 10g | Release date: 2025/10/27 |
Product Introduction
Bioactivity
| Name | Propargyl-PEG1-acid |
| Description | Propargyl-PEG1-acid, a PEG-based PROTAC linker, enables the synthesis of BTK-CRBN PROTACs, specifically Ibrutinib-based PROTAC 4 and PROTAC 5. At a concentration of 10 μM, PROTAC 5 facilitates the degradation of BTK and induces the degradation of CSK, LYN, and LAT2[1]. |
| In vitro | BTK-CRBN PROTACs function as stoichiometric degraders, leading to the degradation of the BTK protein. This process occurs through the recruitment of the cereblon E3 ligases family[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | Propargyl-PEG1-acid | Propargyl-PEG-1-acid | PropargylPEG1acid | Propargyl PEG1 acid | PEGs |
| Inhibitors Related | N-(4-Carboxycyclohexylmethyl)maleimide | Boc-C16-COOH | Pentaethylene glycol | Azido-PEG1 | Diethylene glycol bis(p-toluenesulfonate) | 6-Maleimidocapronic acid | Triethylene glycol | Bis-Tos-PEG4 | 11-Aminoundecanoic acid | 1,3-Dibromo-5,5-dimethylhydantoin | m-PEG12-NHS ester | Tetraethylene glycol |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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