Product Details
| Product Name:
RD3-0028 |
CAS No.:
3886-39-3 |
| Supply Ability:
10g |
Release date:
2025/07/31 |
Product Introduction
Bioactivity
| Name | RD3-0028 |
| Description | RD3-0028 is a potent and selective RSV replication inhibitor with an EC50 of 4.5 μM. |
| In vitro | RD3-0028 exhibits an effective concentration (EC50) of 4.5 μM and a significantly lower cytotoxicity, with a 50% cytotoxic concentration (CC50) of 271.0μM, outperforming ribavirin. It lacks inhibitory effects on the replication of measles virus, influenza A virus, herpes simplex virus types 1 and 2, and human cytomegalovirus. However, RD3-0028 effectively inhibits various RSV strains at concentrations ranging from 4.5 to 11.0 μM, as determined by the MTT method, demonstrating superior efficacy to ribavirin with lower EC50 values against these strains[1]. |
| In vivo | Aerosols from reservoirs containing RD3-0028 (7 mg/mL; 2 h twice daily for 3 days) significantly reduce the pulmonary titer in RSV-infected mice, demonstrating that the minimal effective dose of RD3-0028 is considerably less than that of ribavirin, the only compound currently available for RSV disease. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | RSV | RD3-0028 | RD-3-0028 | RD30028 | RD3 0028 |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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