![(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid](/ProductImageEN/2023-07/Large/a5e00ee7-4bf1-4845-8971-3e7efe039aca.gif) 
                        Product Details
| Product Name: (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid | CAS No.: 1012341-48-8 | 
| Min. Order: 1kg | Purity: 99% | 
| Supply Ability: 500KG | Release date: 2025/07/08 | 
- (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid 
- (R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid is a white to off-white solid with a molecular weight of 409.52 g/mol and a molecular formula of C25H31NO4.
- It has a boiling point of 562.7±50.0 °C and a density of 1.081±0.06 g/cm3.
- It has a pKa of 11.14±0.46  and is soluble in tetrahydrofuran.
- It is also known as (R)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpent-2-enoate.
- Its use is as an intermediate for sacubitril valsartan sodium, and introduce the use of sacubitril valsartan sodium.
- Sacubitril valsartan sodium is a combination drug that contains sacubitril, a neprilysin inhibitor, and valsartan, an angiotensin II receptor blocker.
- It is used to treat heart failure with reduced ejection fraction.
- It works by enhancing the protective neurohormonal systems of the heart and inhibiting the harmful ones.
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                                    CAS:1012341-50-2 $0.00 / 1kg 
Recommended supplier
| Product name | Price | Suppliers | Update time | |
|---|---|---|---|---|
| $0.00/25kg | VIP1Y | Shaanxi Dideu New Materials Co. Ltd | 2025-03-05 | |
| $1.00/1KG | VIP6Y | Career Henan Chemical Co | 2020-01-16 | |
| $100.00/1KG | VIP8Y | Career Henan Chemical Co | 2018-07-27 | |
| $1.00/1KG | VIP6Y | Career Henan Chemical Co | 2020-01-02 | 
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![(R,E)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoic acid](/ProductImageEN/2023-07/Small/a5e00ee7-4bf1-4845-8971-3e7efe039aca.gif) 
                                        ![(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpentanoic acid](https://img.chemicalbook.com/ProductImageEN/2023-06/Large/69a62560-d3bd-4ec3-bfcd-f26c9768c5bd.gif) 
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