SKF38393 hydrobromide NEW
| Price | $128 | $259 | $569 |
| Package | 10mg | 25mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-09-16 |
Product Details
| Product Name: SKF38393 hydrobromide | CAS No.: 20012-10-6 |
| Purity: 98.99% | Supply Ability: 10g |
| Release date: 2025/09/16 |
Product Introduction
Bioactivity
| Name | SKF38393 hydrobromide |
| Description | SKF38393 hydrobromide is the salt form of SKF38393.SKF38393 is a dopamine D1 receptor agonist that increases the expression of Shati/Nat8L mRNA in the NAc of mice; increases the frequency of 5-hydroxytryptamine and n -methyl- D -aspartate-induced locomotion-associated ruptures in astrocytes; can mimic the dopamine-induced inhibition of colonic motility in mice; can promote locust swarming |
| In vitro | Methods: To assess the role of dopamine receptor subtypes in the initiation of behavioral sensitization to cocaine, the partial D1 agonist SKF-38393 (0.01-1.0 μg/side), the D2/3 agonist quinpirole (0.1-1.0 μg/side), or saline was infused once daily into the ventral tegmental area (VTA) or nucleus accumbens shell over 3 days. Results: 1.0 μg/side SKF-38393 infusion into the nucleus accumbens shell produced significant behavioral hyperactivity after both the first and last daily infusions, with no significant differences in behavioral responses between days; repeated administration of SKF-38393 into the VTA resulted in sensitization to the locomotor activating effects of cocaine.[6] |
| In vivo | Methods: To assess the role of dopamine receptor subtypes in the initiation of behavioral sensitization to cocaine, the partial D1 agonist SKF38393 hydrobromide (0.01-1.0 μg/side), the D2/3 agonist quinpirole (0.1-1.0 μg/side), or saline was infused once daily into the ventral tegmental area (VTA) or nucleus accumbens shell over 3 days. Results: 1.0 μg/side SKF38393 hydrobromide infusion into the nucleus accumbens shell produced significant behavioral hyperactivity after both the first and last daily infusions, with no significant differences in behavioral responses between days; repeated administration of SKF38393 hydrobromide into the VTA resulted in sensitization to the locomotor activating effects of cocaine.[1] |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 10 mg/mL (29.74 mM), Sonication is recommended. |
| Keywords | SKF-38393 Hydrobromide | SKF38393 Hydrobromide |
| Inhibitors Related | Olanzapine | Clozapine N-Oxide | Mirtazapine | Promazine hydrochloride | Octopamine hydrochloride | Benserazide hydrochloride | L-DOPA | Citicoline | Oxolinic acid | Mianserin hydrochloride | Doxepin hydrochloride | Fluphenazine dihydrochloride |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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