Tetraphenylporphyrin Tetrasulfonic Acid Hydrate NEW

Tetraphenylporphyrin Tetrasulfonic Acid Hydrate

Modify Date: 2024-01-02 18:21:14

Tetraphenylporphyrin Tetrasulfonic Acid Hydrate structure	Common Name	Tetraphenylporphyrin Tetrasulfonic Acid Hydrate
	CAS Number	35218-75-8	Molecular Weight	934.989
	Density	1.6±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C44H30N4O12S4	Melting Point	N/A
	MSDS	ChineseUSA	Flash Point	N/A
	Symbol	GHS07	Signal Word	Warning

Purity		Quantity		Budget		Inquiry

Use of Tetraphenylporphyrin Tetrasulfonic Acid Hydrate TPPS can be used as a non-cytotoxic probe for detecting tumor location[1].

• Properties

• Articles30

• Spectrum

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 Names

Name	tpps
Synonym	More Synonyms

  Biological Activity

Description	TPPS can be used as a non-cytotoxic probe for detecting tumor location[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	TPPS (0-20 μg/mL) shows no toxicity in Vero and HEp-2 cells in vitro and predominantly locates in the soluble and protein fractions in cells[1].
In Vivo	TPPS4 shows the highest tumor to tissue ratios after 96 hours injection with a dose dependent manner[2]. TPPS4 appears to be cleared through the kidneys and absolute concentrations there are reduced with increasing time after injection[2].
References	[1]. Austen JD, et al. Intracellular localization of meso-Tetra(p-sulfophenyl)porphine: a potential tumor localizing agent. Cancer Treat Rep. 1978 Apr;62(4):511-8. [2]. https://pubmed.ncbi.nlm.nih.gov/201378/

 Chemical & Physical Properties

Density	1.6±0.1 g/cm3
Molecular Formula	C44H30N4O12S4
Molecular Weight	934.989
Exact Mass	934.074280
PSA	307.30000
LogP	5.01
Index of Refraction	1.724

 MSDS

MSDS(Chinese)

 Safety Information

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H315-H319-H335
Precautionary Statements	P261-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi
Risk Phrases	R36/37/38
Safety Phrases	S26
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	DB7339000

 Synthetic Route

Total: 1 Page

tetraphenylporphyrin CAS#:917-23-7 ~% Tetraphenylporp... CAS#:35218-75-8

Literature: Journal of the Chemical Society, Faraday Transactions, , vol. 89, # 3 p. 495 - 502

tetra(4-fluoros... CAS#:88289-00-3 ~% Tetraphenylporp... CAS#:35218-75-8

Literature: Journal of Organic Chemistry USSR (English Translation), , vol. 28, # 12.1 p. 1987 - 1994 Zhurnal Organicheskoi Khimii, , vol. 28, # 12 p. 2464 - 2472

 Articles30

More Articles

Femtosecond to second studies of a water-soluble porphyrin derivative in chemical and biological nanocavities. Langmuir 28(9) , 4363-72, (2012) The interactions of 5,10,15,20-tetrakis(4-sulfonatophenyl)-porphyrin (TSPP) with a quaternary ammonium modified β-cyclodextrin (QA-β-CD) and human serum albumin (HSA) protein in aqueous solutions at p...	Detail
Preferential solvation and solvation shell composition of free base and protonated 5, 10, 15, 20-tetrakis(4-sulfonatophenyl)porphyrin in aqueous organic mixed solvents. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 83(1) , 213-20, (2011) The solvatochromic properties of the free base and the protonated 5, 10, 15, 20-tetrakis(4-sulfonatophenyl)porphyrin (TPPS) were studied in pure water, methanol, ethanol (protic solvents), dimethylsul...	Detail
Interaction of monosulfonate tetraphenyl porphyrin (H2TPPS1) with plant-esterase: determination of the binding mechanism by spectroscopic methods. Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 78(5) , 1349-55, (2011) The interaction of monosulfonate tetraphenyl porphyrin (H(2)TPPS(1)) with plant-esterase was investigated using fluorescence and UV-vis absorption spectroscopy. Fluorescence quenching, from which the ..

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