Thymulin NEW
| Price | $39 | $89 | $135 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2026-02-02 |
Product Details
| Product Name: Thymulin | CAS No.: 63958-90-7 |
| Purity: 99.56% | Supply Ability: 10g |
| Release date: 2026/02/02 |
Product Introduction
Bioactivity
| Name | Thymulin |
| Description | Thymulin is a peptide hormone which is mainly produced by thymic epithelial cells and it has immune-modulatory and anti-inflammatory effects |
| In vitro | The effects of different doses and various timings of thymulin intraperitoneal administration on spinal microglial activity and intracellular pathways in an inflammatory rat model of Complete Freund's adjuvant (CFA).?Thymulin treatment was implemented following CFA-induced inflammation for 21 days.?After conducting behavioral tests (edema and hyperalgesia), the cellular and molecular aspects were examined to detect the thymulin effect on inflammatory factors and microglial activity.?Demonstrated that thymulin treatment notably reduced thermal hyperalgesia and paw edema induced by CFA.?Furthermore, molecular investigations showed that thymulin reduced CFA-induced activation of microglia cells, phosphorylation of p38 MAPK and the production of spinal pro-inflammatory cytokines (TNF-α, IL-6) during the study.?Results suggest that thymulin treatment attenuates CFA-induced inflammation.?This effect may be mediated by inhibition of spinal microglia and production of central inflammatory mediators which seems to be associated with the ability of thymulin to reduce p38 MAPK phosphorylation.?These data provide evidence of the anti-hyperalgesic effect of thymulin on inflammatory pain and characterize some of the underlying spinal mechanisms[1]. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O : 10 mM, Sonication is recommended. DMSO : Insoluble |
| Keywords | Thymulin | Inflammationrelated | Inflammation related | Immunologyrelated | Immunology/Inflammation related | Immunology related |
| Inhibitors Related | TBHQ | Urea | L-Cysteine | β-Glycerophosphate disodium salt pentahydrate | 4-Methylbenzylidene camphor | Lactose | Lidocaine hydrochloride | Tauroursodeoxycholate | Propoxur | Gluconate Calcium | Gluconate sodium | β-Glycerophosphate disodium salt hydrate |
| Related Compound Libraries | Bioactive Compound Library | Kinase Inhibitor Library | Peptide Compound Library | Natural Product Library | NO PAINS Compound Library | Natural Product Library for HTS | Immunology/Inflammation Compound Library | Anti-Aging Compound Library | Bioactive Compounds Library Max | Anti-Cancer Compound Library | Human Metabolite Library | MAPK Inhibitor Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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