TT-10 NEW
| Price | $34 | $80 | $128 |
| Package | 1mg | 5mg | 10mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-11-09 |
Product Details
| Product Name: TT-10 | CAS No.: 2230640-94-3 |
| Purity: 99.29% | Supply Ability: 10g |
| Release date: 2025/11/09 |
Product Introduction
Bioactivity
| Name | TT-10 |
| Description | TT-10 (TAZ-K), an activator of YES-associated protein (YAP)-transcriptional enhancer factor domain (TEAD) activity, has potential application in heart disease research, specifically for conditions characterized by loss of cardiomyocytes. |
| In vitro | TT-10 (10 μmol/L ; 48 h) significantly promoted cell cycle activation and cell division of human induced pluripotent stem cell (hiPSC) derived cardiomyocytes (hiPSCM).[1] |
| In vivo | TT-10 (2 μM, 10 μM, 20 μM, or 100 μM ; 48 h ; intraperitoneal injections) was administered to infarcted mouse hearts, the treatment promoted cardiomyocyte proliferation and was associated with declines in infarct size 1 week after administration, but cardiac function worsened at later time points.[2] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO : 60 mg/mL (211.75 mM), Sonication is recommended. 2% DMSO+40% PEG300+5% Tween 80+53% Saline : 1.25 mg/mL (4.41 mM) |
| Keywords | YAP–TEAD | TT-10 | TT10 | TT 10 |
| Inhibitors Related | AICAR | IK-930 | MY-1076 | Verteporfin | YAP-TEAD-IN-3 | DC-TEADin02 | MSC-4106 | VT103 | VT107 | PY-60 | VT104 | MYF-01-37 |
| Related Compound Libraries | Anti-Lung Cancer Compound Library | Bioactive Compound Library | Anti-Cancer Clinical Compound Library | Drug Repurposing Compound Library | Anti-Cardiovascular Disease Compound Library | Stem Cell Differentiation Compound Library | Clinical Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Anti-Cancer Compound Library | Anti-Cancer Drug Library | Anti-Cancer Active Compound Library |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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