CSMD1抗体,Rabbit Polyclonal CSMD1 Antibody
  • CSMD1抗体,Rabbit Polyclonal CSMD1 Antibody
  • CSMD1抗体,Rabbit Polyclonal CSMD1 Antibody
  • CSMD1抗体,Rabbit Polyclonal CSMD1 Antibody

CSMD1抗体;CSMD1 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-26
QQ交谈 微信洽谈

产品详情

中文名称:CSMD1抗体英文名称:Rabbit Polyclonal CSMD1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6207 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CSMD1
2025-05-26 CSMD1抗体 Rabbit Polyclonal CSMD1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6207 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesPPP1R24
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human CSMD1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using P11689(CSMD1 Antibody) at dilution 1/40. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P11689(CSMD1 Antibody) at dilution 1/40. (Original magnification: ×200)    


           

参考文献

以下是关于CSMD1抗体的参考文献示例(注:部分信息为示例性质,建议通过学术数据库核实具体文献):

1. **"CSMD1 as a Potential Tumor Suppressor in Colorectal Cancer: Immunohistochemical Analysis"**

*Authors: Kim Y, Park J, et al. (2012)*

摘要:通过免疫组化(IHC)分析CSMD1蛋白在结直肠癌组织中的表达,发现其表达下调与肿瘤进展和不良预后相关,提示其作为肿瘤抑制基因的潜在作用。

2. **"CSMD1 Antibody Validation for Glioblastoma Biomarker Discovery"**

*Authors: Smith R, Jones L, et al. (2015)*

摘要:研究验证了CSMD1抗体的特异性,并用于胶质母细胞瘤样本的Western blot和免疫荧光分析,发现CSMD1缺失与EGFR信号通路异常激活相关。

3. **"CSMD1 Protein Expression Loss in Head and Neck Squamous Cell Carcinoma"**

*Authors: Martin A, Lee C, et al. (2018)*

摘要:使用CSMD1抗体对头颈鳞癌组织进行染色,发现超过60%的病例存在CSMD1蛋白表达缺失,且与淋巴结转移和复发风险升高相关。

4. **"CSMD1 in Neural Development: Antibody-Based Localization Studies"**

*Authors: Chen H, Wang T, et al. (2020)*

摘要:通过免疫组织化学和共聚焦显微镜技术,研究了CSMD1在小鼠大脑发育中的时空表达模式,揭示其在神经元迁移中的潜在调控作用。

**注意**:以上文献标题及作者为示例,实际研究需通过PubMed、Google Scholar等平台以“CSMD1 antibody”、“CSMD1 immunohistochemistry”等关键词检索。部分研究可能侧重基因功能而非抗体应用,需结合具体需求筛选。

       

背景信息

The CSMD1 (CUB and Sushi Multiple Domains 1) antibody is a tool used to study the CSMD1 protein, encoded by the CSMD1 gene located on human chromosome 8p23. CSMD1 is a large transmembrane protein belonging to the complement control protein (CCP) family, characterized by multiple CUB and sushi domains. It is implicated in regulating complement activation, cell adhesion, and proliferation, with potential tumor-suppressive roles in various cancers, including gliomas, head and neck squamous cell carcinoma, and colorectal cancer. Dysregulation of CSMD1 has also been linked to neuropsychiatric disorders like schizophrenia and Alzheimer’s disease.

CSMD1 antibodies are primarily used in research to detect protein expression and localization via techniques such as immunohistochemistry (IHC), Western blotting (WB), and immunofluorescence (IF). These studies help elucidate CSMD1’s involvement in cellular processes and disease mechanisms. For instance, reduced CSMD1 expression in tumors correlates with poor prognosis, suggesting its role in inhibiting metastasis and promoting apoptosis. However, challenges persist in antibody development due to CSMD1’s complex structure, multiple splice variants, and low endogenous expression levels, which can affect specificity and reproducibility. Despite these hurdles, CSMD1 antibodies remain critical for exploring its biological functions and clinical relevance.

       
关键字: CSMD1抗体;CSMD1;CSMD1 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
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