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ChemicalBook >> CAS DataBase List >> NSC 23766 TETRAHYDROCHLORIDE

NSC 23766 TETRAHYDROCHLORIDE

NSC 23766 TETRAHYDROCHLORIDE price.
  • $129 - $1900
  • Product name: NSC 23766 TETRAHYDROCHLORIDE
  • CAS: 733767-34-5
  • MF: C24H35N7
  • MW: 421.58
  • EINECS:
  • MDL Number:MFCD07848572
  • Synonyms:NSC 23766 TETRAHYDROCHLORIDE;N6-[2-[[4-(DIETHYLAMINO)-1-METHYLBUTYL]AMINO]-6-METHYL-4-PYRIMIDINYL]-2-METHYL-4,6-QUINOLINEDIAMINE TRIHYDROCHLORIDE;NSC 23766;NSC23766;NSC 23766;CS-1187;CS-594;NSC-23766 free base;N6-[2-(4-Diethylamino-1-methylbutylamino)-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine tetrahydrochloride
Price5 Properties Safety Information Description
5 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • DC Chemicals
  • Tocris
Package
  • 50
  • 5MG
  • 250mg
  • 10
  • 1g
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0002397
  • Product descriptionNSC 23766 95.00%
  • Packaging5MG
  • Price$503.57
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7963
  • Product descriptionNSC-23766freebase >98%
  • Packaging250mg
  • Price$1000
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC7963
  • Product descriptionNSC-23766freebase >98%
  • Packaging1g
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2161
  • Product descriptionNSC 23766 ≥99%(HPLC)
  • Packaging10
  • Price$166
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2161
  • Product descriptionNSC 23766 ≥99%(HPLC)
  • Packaging50
  • Price$703
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0002397 NSC 23766 95.00% 5MG $503.57 2021-12-16 Buy
DC Chemicals DC7963 NSC-23766freebase >98% 250mg $1000 2021-12-16 Buy
DC Chemicals DC7963 NSC-23766freebase >98% 1g $1900 2021-12-16 Buy
Tocris 2161 NSC 23766 ≥99%(HPLC) 10 $166 2021-12-16 Buy
Tocris 2161 NSC 23766 ≥99%(HPLC) 50 $703 2021-12-16 Buy

Properties

storage temp. :Desiccate at RT
solubility :Soluble in DMSO (50 mg/ml); Water (50 mg/ml)
form :White powder solid.
color :White
Water Solubility :Soluble in water.
Sensitive :Light Sensitive & Hygroscopic
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20°C for up to 3 months.

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

The compound blocks activation by the guanine nucleotide exchange factors Trio and Tiam1, but does not affect interactions with RhoA or Cdc42. NSC23766 blocks ADP-mediated platelet aggregation. Inhibition of Rac1 by NSC23766 restores sensitivity to trastuzumab by restoring down-regulation of ErbB2. Membrane type 1-matrix metalloproteinases (MT-1MMP) expression in CB CD34+ cells has been reported to decrease in the presence of NSC 23766. Silveta compress investigations indicate that NSC 23766 depolarizes endomembrane cycling, altered polar adhesive secretion, and tip growth.

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Suppliers and manufacturers

TargetMol Chemicals Inc.
NSC 23766
$49.00 /2mg
NSC 23766 CAS:733767-34-5
InvivoChem
Coresyn Pharmatech Co., Ltd.
Aladdin Scientific
Amadis Chemical Company Limited 3B Pharmachem (Wuhan) International Co.,Ltd. VDM Biochemicals QINGDAO CARELONGPHARMATECH CO.,LTD Shanghai Aladdin Bio-Chem Technology Co.,LTD AdooQ Bioscience CHINA