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ChemicalBook >> CAS DataBase List >> CAY10505

CAY10505

CAY10505 price.
  • $41 - $1963.5
  • Product name: CAY10505
  • CAS: 328960-84-5
  • MF: C14H8FNO3S
  • MW: 289.28
  • EINECS:
  • MDL Number:MFCD18382079
  • Synonyms:(5E)-5-{[5-(4-fluorophenyl)furan-2-yl]methylidene}-1,3-thiazolidine-2,4-dione;5-((5-(4-Fluorophenyl)furan-2-yl)methylene)thiazolidine-2,4-dione;2,4-Thiazolidinedione, 5-[[5-(4-fluorophenyl)-2-furanyl]methylene]-;POSH-IN-1
Price20 Properties Safety Information Description
20 prices
Selected condition：
Brand
  • aablocks
  • ACHEMBLOCK
  • AK Scientific
  • American Custom Chemicals Corporation
  • Biosynth
  • Cayman Chemical
  • ChemScene
Package
  • 2mg
  • 5mg
  • 10MG
  • 25MG
  • 50mg
  • 100MG
  • 250MG
  • Manufactureraablocks
  • Product numberAA00C0TI
  • Product descriptionCAY10505 ≥98%
  • Packaging5mg
  • Price$41
  • Updated2026-05-28
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD279636
  • Product descriptionPOSH-IN-1 98%
  • Packaging25MG
  • Price$185
  • Updated2026-05-27
  • Buy
  • ManufacturerACHEMBLOCK
  • Product numberAD279636
  • Product descriptionPOSH-IN-1 98%
  • Packaging100MG
  • Price$555
  • Updated2026-05-27
  • Buy
  • ManufacturerAK Scientific
  • Product number1420AH
  • Product description5-((5-(4-Fluorophenyl)-2-furanyl)methylene)-2,4-thiazolidinedione
  • Packaging50mg
  • Price$413
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0104975
  • Product description5-((5-(4-FLUOROPHENYL)-2-FURANYL)METHYLENE)-2,4-THIAZOLIDINEDIONE 95.00%
  • Packaging10MG
  • Price$739.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0104975
  • Product description5-((5-(4-FLUOROPHENYL)-2-FURANYL)METHYLENE)-2,4-THIAZOLIDINEDIONE 95.00%
  • Packaging25MG
  • Price$750.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0104975
  • Product description5-((5-(4-FLUOROPHENYL)-2-FURANYL)METHYLENE)-2,4-THIAZOLIDINEDIONE 95.00%
  • Packaging100MG
  • Price$1871.1
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0104975
  • Product description5-((5-(4-FLUOROPHENYL)-2-FURANYL)METHYLENE)-2,4-THIAZOLIDINEDIONE 95.00%
  • Packaging250MG
  • Price$1963.5
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFC137603
  • Product descriptionCAY10505
  • Packaging25mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFC137603
  • Product descriptionCAY10505
  • Packaging5mg
  • Price$110
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFC137603
  • Product descriptionCAY10505
  • Packaging10mg
  • Price$170
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFC137603
  • Product descriptionCAY10505
  • Packaging2mg
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth
  • Product numberFC137603
  • Product descriptionCAY10505
  • Packaging50mg
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009078
  • Product descriptionCAY10505 ≥98%
  • Packaging10mg
  • Price$75
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009078
  • Product descriptionCAY10505 ≥98%
  • Packaging25mg
  • Price$178
  • Updated2026-04-30
  • Buy
  • ManufacturerCayman Chemical
  • Product number10009078
  • Product descriptionCAY10505 ≥98%
  • Packaging5mg
  • Price$41
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA00C0TI CAY10505 ≥98% 5mg $41 2026-05-28 Buy
ACHEMBLOCK AD279636 POSH-IN-1 98% 25MG $185 2026-05-27 Buy
ACHEMBLOCK AD279636 POSH-IN-1 98% 100MG $555 2026-05-27 Buy
AK Scientific 1420AH 5-((5-(4-Fluorophenyl)-2-furanyl)methylene)-2,4-thiazolidinedione 50mg $413 2021-12-16 Buy
American Custom Chemicals Corporation HCH0104975 5-((5-(4-FLUOROPHENYL)-2-FURANYL)METHYLENE)-2,4-THIAZOLIDINEDIONE 95.00% 10MG $739.2 2021-12-16 Buy
American Custom Chemicals Corporation HCH0104975 5-((5-(4-FLUOROPHENYL)-2-FURANYL)METHYLENE)-2,4-THIAZOLIDINEDIONE 95.00% 25MG $750.75 2021-12-16 Buy
American Custom Chemicals Corporation HCH0104975 5-((5-(4-FLUOROPHENYL)-2-FURANYL)METHYLENE)-2,4-THIAZOLIDINEDIONE 95.00% 100MG $1871.1 2021-12-16 Buy
American Custom Chemicals Corporation HCH0104975 5-((5-(4-FLUOROPHENYL)-2-FURANYL)METHYLENE)-2,4-THIAZOLIDINEDIONE 95.00% 250MG $1963.5 2021-12-16 Buy
Biosynth FC137603 CAY10505 25mg $385 2021-12-16 Buy
Biosynth FC137603 CAY10505 5mg $110 2021-12-16 Buy
Biosynth FC137603 CAY10505 10mg $170 2021-12-16 Buy
Biosynth FC137603 CAY10505 2mg $55 2021-12-16 Buy
Biosynth FC137603 CAY10505 50mg $600 2021-12-16 Buy
Cayman Chemical 10009078 CAY10505 ≥98% 10mg $75 2026-04-30 Buy
Cayman Chemical 10009078 CAY10505 ≥98% 25mg $178 2026-04-30 Buy
Cayman Chemical 10009078 CAY10505 ≥98% 5mg $41 2026-04-30 Buy
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Properties

Density :1.466±0.06 g/cm3(Predicted)
solubility :DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2)(1:5): 0.15 mg/ml
form :A crystalline solid
pka :6.21±0.20(Predicted)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Phosphoinositide 3-kinase γ (PI3Kγ), expressed primarily in hematopoietic cells, plays several important roles in immunity. CAY10505 is a potent inhibitor of PI3K, selectively inhibiting the γ isoform (IC50 = 30 nM) better than the α, β, and δ isoforms (IC50 = 0.94, 20, and 20 μM, respectively).1 Tested against a panel of 80 other kinases, CAY10505 significantly inhibits only the unrelated casein kinase 2 (CK2, IC50 = 20 nM). It also inhibits the phosphorylation of the PI3K substrate PKB/Akt in mouse macrophages (IC50 = 228 nM).1 Oral administration of CAY10505 reduces neutrophil recruitment in mice to an extent that is comparable to that observed in PI3Kγ-deficient mice.1

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Shanghai EFE Biological Technology Co., Ltd. Jinan Jiuli Biotechnology Co. , Ltd. TargetMol Chemicals Inc.