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ChemicalBook >> CAS DataBase List >> (+)-JQ-1

(+)-JQ-1

(+)-JQ-1 price.
  • $9 - $5000
  • Product name: (+)-JQ-1
  • CAS: 1268524-70-4
  • MF: C23H25ClN4O2S
  • MW: 456.99
  • EINECS:
  • MDL Number:MFCD22683748
  • Synonyms:(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate;(+)-JQ-1;(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thienol[3,2-f][1,2,4]troazolo[4,3-a][1,4]diazepin-6-yl)acetate[(+)-6];(+)-JQ1,(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate;(+)-JQ1,(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate CAS：;BroModoMain Inhibitor, (+)-JQ1;CS-799;(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetic acid 1,1-dimethylethyl ester
Price97 Properties Safety Information Description
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  • aablocks
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  • 10mM(in1mLDMSO)
  • 10mM*1mLinDMSO(Solid+Solvent)
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  • 1mg
  • 10mM*1mLinDMSO
  • 10mM*1mLinDMSO(Solution)
  • 2mg
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98%
  • Packaging50mg
  • Price$20
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate >97%
  • Packaging100mg
  • Price$25
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate >97%
  • Packaging250mg
  • Price$45
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98%
  • Packaging500mg
  • Price$75
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98%
  • Packaging1g
  • Price$95
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98%
  • Packaging5g
  • Price$266
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98%
  • Packaging10g
  • Price$464
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98%
  • Packaging25mg
  • Price$17
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate ≥98%(HPLC)
  • Packaging5mg
  • Price$10
  • Updated2026-05-25
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  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98%
  • Packaging10mg
  • Price$10
  • Updated2026-05-25
  • Buy
  • Manufactureraablocks
  • Product numberAA000TA7
  • Product description(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98%
  • Packaging1mg
  • Price$9
  • Updated2026-05-25
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  • ManufacturerACHEMBLOCK
  • Product numberL14965
  • Product descriptionJQ 1 98%
  • Packaging5G
  • Price$845
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL14965
  • Product descriptionJQ 1 98%
  • Packaging1G
  • Price$190
  • Updated2026-05-27
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  • ManufacturerACHEMBLOCK
  • Product numberL14965
  • Product descriptionJQ 1 98%
  • Packaging100MG
  • Price$40
  • Updated2026-05-27
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-3004-M005
  • Product description(+)-JQ1 ≥95%
  • Packaging5mg
  • Price$227
  • Updated2026-05-06
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberSYN-3004-M010
  • Product description(+)-JQ1 ≥95%
  • Packaging10mg
  • Price$394
  • Updated2026-05-06
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98% 50mg $20 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate >97% 100mg $25 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate >97% 250mg $45 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98% 500mg $75 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98% 1g $95 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98% 5g $266 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98% 10g $464 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98% 25mg $17 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate ≥98%(HPLC) 5mg $10 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98% 10mg $10 2026-05-25 Buy
aablocks AA000TA7 (S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate 98% 1mg $9 2026-05-25 Buy
ACHEMBLOCK L14965 JQ 1 98% 5G $845 2026-05-27 Buy
ACHEMBLOCK L14965 JQ 1 98% 1G $190 2026-05-27 Buy
ACHEMBLOCK L14965 JQ 1 98% 100MG $40 2026-05-27 Buy
Adipogen Life Sciences SYN-3004-M005 (+)-JQ1 ≥95% 5mg $227 2026-05-06 Buy
Adipogen Life Sciences SYN-3004-M010 (+)-JQ1 ≥95% 10mg $394 2026-05-06 Buy
Next Last

Properties

Melting point :>205°C (dec.)
Boiling point :610.4±65.0 °C(Predicted)
Density :1.33
storage temp. :2-8°C
solubility :DMSO: soluble20mg/mL, clear
pka :2.05±0.60(Predicted)
form :powder
color :white to beige
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 2 months.
InChI :InChI=1S/C23H25ClN4O2S/c1-12-13(2)31-22-19(12)20(15-7-9-16(24)10-8-15)25-17(11-18(29)30-23(4,5)6)21-27-26-14(3)28(21)22/h7-10,17H,11H2,1-6H3/t17-/m0/s1
InChIKey :DNVXATUJJDPFDM-KRWDZBQOSA-N
SMILES :N12C(C)=NN=C1[C@H](CC(OC(C)(C)C)=O)N=C(C1=CC=C(Cl)C=C1)C1C(C)=C(C)SC=12

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H332 Harmful if inhaled Acute toxicity,inhalation Category 4 Warning P261, P271, P304+P340, P312
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. JQ1 displaces BET proteins from chromatin by competitively binding to the acetyl-lysine recognition pocket of BET bromodomains. Enantiomerically pure (+)-JQ1 binds to BRD4 bromodomains 1 and 2 with Kd values of ~50 and 90 nM, respectively, whereas the (?)-JQ1 stereoisomer has no appreciable affinity to BET bromodomains. JQ1 has been used as a chemical probe to investigate the role of BET bromodomains in the transcriptional regulation of oncogenesis. See the Structural Genomics Consortium (SGC) website for more information.

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Suppliers and manufacturers

career henan chemical co
(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
$1.00
(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate CAS:1268524-70-4
career henan chemical co
(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate
$7.00
(S)-tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-triMethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate CAS:1268524-70-4
TargetMol Chemicals Inc.
(+)-JQ-1
$30.00
(+)-JQ-1 CAS:1268524-70-4
Capot Chemical Co.,Ltd.
Zhejiang ZETian Fine Chemicals Co. LTD
CONIER CHEM AND PHARMA LIMITED
Hefei Hangang Pharmaceutical Technology Co., Ltd.
Career Henan Chemica Co
Dideu Industries Group Limited
BOC Sciences