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ChemicalBook >> CAS DataBase List >> OSU-03012

OSU-03012

OSU-03012 price.
  • $50 - $5833
  • Product name: OSU-03012
  • CAS: 742112-33-0
  • MF: C26H19F3N4O
  • MW: 460.45
  • EINECS:-0
  • MDL Number:MFCD12912272
  • Synonyms:OSU-03012, >=98%;OSU-03012 (AR-12);AR-12;2-amino-N-(4-(5-(phenanthren-2-yl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenyl)acetamide;2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide OSU-03012;N/AAR-12;OSU-03012;2-Amino-N-[4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]phenyl]acetamide
Price25 Properties Safety Information Description
25 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Axon Medchem
  • Biorbyt Ltd
  • Cayman Chemical
  • Crysdot
  • DC Chemicals
  • Labseeker
  • Matrix Scientific
  • Tocris
  • TRC
Package
  • 50
  • 10
  • 5mg
  • 10mg
  • 20mg
  • 25MG
  • 50mg
  • 100mg
  • 250mg
  • 1000mg
  • 1g
  • 5g
  • 10g
  • ManufacturerAK Scientific
  • Product numberY0267
  • Product descriptionOSU-03012
  • Packaging5mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000876
  • Product descriptionOSU-03012 95.00%
  • Packaging5MG
  • Price$200.2
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0000876
  • Product descriptionOSU-03012 95.00%
  • Packaging25MG
  • Price$808.5
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2846
  • Product descriptionOSU-03012(AR-12)
  • Packaging5mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN60198
  • Product descriptionOSU-03012(AR-12) ≥98%
  • Packaging20mg
  • Price$378
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2525
  • Product descriptionOSU03012 99%
  • Packaging10mg
  • Price$104.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2525
  • Product descriptionOSU03012 99%
  • Packaging50mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181075
  • Product descriptionOSU-03012 >98%
  • Packaging100mg
  • Price$615.4
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181075
  • Product descriptionOSU-03012 >98%
  • Packaging250mg
  • Price$1208.7
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb181075
  • Product descriptionOSU-03012 >98%
  • Packaging1000mg
  • Price$2395.3
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008005
  • Product descriptionOSU03012
  • Packaging5mg
  • Price$73
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008005
  • Product descriptionOSU03012
  • Packaging10mg
  • Price$116
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008005
  • Product descriptionOSU03012
  • Packaging50mg
  • Price$502
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number10008005
  • Product descriptionOSU03012
  • Packaging100mg
  • Price$789
  • Updated2024-03-01
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000909
  • Product descriptionOSU-03012 98+%
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000909
  • Product descriptionOSU-03012 98+%
  • Packaging25mg
  • Price$160
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0267 OSU-03012 5mg $70 2021-12-16 Buy
American Custom Chemicals Corporation INB0000876 OSU-03012 95.00% 5MG $200.2 2021-12-16 Buy
American Custom Chemicals Corporation INB0000876 OSU-03012 95.00% 25MG $808.5 2021-12-16 Buy
ApexBio Technology A2846 OSU-03012(AR-12) 5mg $50 2021-12-16 Buy
Arctom CFN60198 OSU-03012(AR-12) ≥98% 20mg $378 2021-12-16 Buy
Axon Medchem Axon2525 OSU03012 99% 10mg $104.5 2021-12-16 Buy
Axon Medchem Axon2525 OSU03012 99% 50mg $385 2021-12-16 Buy
Biorbyt Ltd orb181075 OSU-03012 >98% 100mg $615.4 2021-12-16 Buy
Biorbyt Ltd orb181075 OSU-03012 >98% 250mg $1208.7 2021-12-16 Buy
Biorbyt Ltd orb181075 OSU-03012 >98% 1000mg $2395.3 2021-12-16 Buy
Cayman Chemical 10008005 OSU03012 5mg $73 2024-03-01 Buy
Cayman Chemical 10008005 OSU03012 10mg $116 2024-03-01 Buy
Cayman Chemical 10008005 OSU03012 50mg $502 2024-03-01 Buy
Cayman Chemical 10008005 OSU03012 100mg $789 2024-03-01 Buy
Crysdot CD31000909 OSU-03012 98+% 10mg $100 2021-12-16 Buy
Crysdot CD31000909 OSU-03012 98+% 25mg $160 2021-12-16 Buy
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Properties

storage temp. :Store at -20°C
solubility :≥23 mg/mL in DMSO; insoluble in H2O; insoluble in EtOH
form :solid
color :White to off-white
CAS DataBase Reference :742112-33-0

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P321 Specific treatment (see … on this label).
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P337+P313 IF eye irritation persists: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Cyclooxygenase-2 (COX-2) appears to play a significant role in the development and progression of cancer and COX-2 inhibitors such as celecoxib exhibit anti-cancer activity. OSU03012 is an analog of celecoxib that exhibits anti-cancer activity in a COX-2-independent manner via inhibition of the phosphatidyl inositol-3-kinase/Akt pathway. It has an IC50 value of 5 μM for inhibition of 3-phosphoinositide-dependent kinase-1, and therefore Akt activation, with no measurable COX-2 inhibition up to 50 μM. OSU03012 is a potent inhibitor of tumor cell growth with an average inhibitory concentration of 1.1 μM across a panel of 60 cancer cell lines. It does not inhibit signal transduction through the mitogen-activated protein kinase (MAPK) pathway. OSU03012 induces apoptosis of chronic lymphocytic leukemia cells independent of bcl-2 overexpression using both caspase-dependent and independent pathways.

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Suppliers and manufacturers

career henan chemical co
OSU-03012
$2.00 /1kg
OSU-03012 CAS:742112-33-0
TargetMol Chemicals Inc.
Osu03012
$31.00 /2mg
Osu03012 CAS:742112-33-0
Capot Chemical Co.,Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner
BOC Sciences
CONIER CHEM AND PHARMA LIMITED
Dideu Industries Group Limited
Hefei Hirisun Pharmatech Co., Ltd
Zhejiang J&C Biological Technology Co.,Limited