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ChemicalBook CAS DataBase List 2-Sulfanyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile
112629-69-3

2-Sulfanyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: sodium; methanol / 0 - 20 °C / Inert atmosphere
2: acetic acid; piperidine / water / 4 h / Inert atmosphere; Reflux

References:

Leung, Euphemia;Pilkington, Lisa I.;van Rensburg, Michelle;Jeon, Chae Yeon;Song, Mirae;Arabshahi, Homayon J.;De Zoysa, Gayan Heruka;Sarojini, Vijayalekshmi;Denny, William A.;Reynisson, Jóhannes;Barker, David [Bioorganic and Medicinal Chemistry,2016,vol. 24,# 5,p. 1142 - 1154]