Methyl 1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxylate synthesis
- Product Name:Methyl 1-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxylate
- CAS Number:133747-62-3
- Molecular formula:C12H12FNO3
- Molecular Weight:237.23
67-56-1
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56617-43-7
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133747-62-3
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Yield:-
Reaction Conditions:
sulfuric acid in dichloromethane;Heating / reflux;
Steps:
7.2
Step 2. To l-(4-fluorophenyl)-5-oxopyrrolidine-3-carboxylic acid 51 was added 80 mL Of CH2Cl2, 30 mL of MeOH, and 1.0 mL of concentrated H2SO4. After heating at reflux overnight, the mixture concentrated and triturated with water to give methyl 1 -(4- fluorophenyl)-5-oxopyrrolidine-3-carboxylate 52.
References:
WO2009/51718,2009,A2 Location in patent:Page/Page column 38
371-40-4
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133747-62-3
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$75.00/1g
67-56-1
758 suppliers
$9.00/25ml
1181406-58-5
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133747-62-3
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$75.00/1g
97-65-4
547 suppliers
$5.00/25g
133747-62-3
20 suppliers
$75.00/1g
56617-43-7
55 suppliers
$27.57/250mgs:
133747-62-3
20 suppliers
$75.00/1g