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Itaconic acid

CAS No.
97-65-4
Chemical Name:
Itaconic acid
Synonyms
METHYLENESUCCINIC ACID;Butanedioic acid, methylene-;itaconic acide;methylene-butanedioicaci;3-CARBOXY-3-BUTENOIC ACID;2-methylidenebutanedioic acid;1-Propene-2,3-dicarboxylic acid;Itaconsure;Yikang acid;ITACONIC ACID
CBNumber:
CB8439347
Molecular Formula:
C5H6O4
Molecular Weight:
130.1
MDL Number:
MFCD00004260
MOL File:
97-65-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-06-24 18:39:39
Product description Number Pack Size Price
Itaconic acid ≥99% I29204 1kg $79.9
Methylenesuccinic acid for synthesis 8.04812 100g $31.2
Methylenesuccinic acid for synthesis 8.04812 500g $44.4
Itaconic acid analytical standard 93598 100mg $95.6
Methylenesuccinic acid for synthesis 8.04812 50kg $1760
More product size

Itaconic acid Properties

Melting point 165-168 °C (lit.)
Boiling point 268°C
Density 1.573 g/mL at 25 °C (lit.)
vapor pressure 0.0000115 Pa (20 °C)
refractive index 1.4980 (estimate)
Flash point 268°C
storage temp. Store below +30°C.
solubility 77.49g/l
pka 3.85(at 25℃)
form Crystalline Powder or Crystals
color White to light beige
Specific Gravity 1.573
Odor Characteristic Odor
PH 3.5(1 mM solution);2.95(10 mM solution);2.43(100 mM solution);
Water Solubility Soluble in water, acetone, methanol, hexane and ethanol. Slightly soluble in benzene, chloroform, carbon disulfide and petroleum ether.
Sensitive Hygroscopic
Merck 14,5242
BRN 1759501
Henry's Law Constant 1.3×106 mol/(m3Pa) at 25℃, Yaws (2003)
Stability Light Sensitive
Cosmetics Ingredients Functions BUFFERING
ANTIMICROBIAL
SKIN CONDITIONING - EMOLLIENT
SKIN CONDITIONING
InChI 1S/C5H6O4/c1-3(5(8)9)2-4(6)7/h1-2H2,(H,6,7)(H,8,9)
InChIKey LVHBHZANLOWSRM-UHFFFAOYSA-N
SMILES OC(=O)CC(=C)C(O)=O
LogP -0.301 at 20℃
Indirect Additives used in Food Contact Substances ITACONIC ACID
FDA 21 CFR 175.105; 175.320; 176.170;176.180; 177.1010; 177.1200;177.1630
CAS DataBase Reference 97-65-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII Q4516562YH
NIST Chemistry Reference Butanedioic acid, methylene-(97-65-4)
EPA Substance Registry System Itaconic acid (97-65-4)
UNSPSC Code 85151701
NACRES NA.24
CAS Number Unlabeled 97-65-4

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)
GHS05
Signal word  Danger
Hazard statements  H318
Precautionary statements  P280-P305+P351+P338+P310
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  1
Autoignition Temperature 430 °C
TSCA  TSCA listed
HS Code  29171990
Storage Class 13 - Non Combustible Solids
Hazard Classifications Eye Dam. 1
Hazardous Substances Data 97-65-4(Hazardous Substances Data)
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
REACH Registrations Active
NFPA 704
0
2 0

Itaconic acid price More Price(83)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I29204 Itaconic acid ≥99% 97-65-4 1kg $79.9 2026-04-30 Buy
Sigma-Aldrich 8.04812 Methylenesuccinic acid for synthesis 97-65-4 100g $31.2 2026-04-30 Buy
Sigma-Aldrich 8.04812 Methylenesuccinic acid for synthesis 97-65-4 500g $44.4 2026-04-30 Buy
Sigma-Aldrich 93598 Itaconic acid analytical standard 97-65-4 100mg $95.6 2026-04-30 Buy
Sigma-Aldrich 8.04812 Methylenesuccinic acid for synthesis 97-65-4 50kg $1760 2026-04-30 Buy
Product number Packaging Price Buy
I29204 1kg $79.9 Buy
8.04812 100g $31.2 Buy
8.04812 500g $44.4 Buy
93598 100mg $95.6 Buy
8.04812 50kg $1760 Buy

Itaconic acid Chemical Properties,Uses,Production

Discovery

Itaconic acid was discovered by Baup in 1837 as a product of the pyrolytic distillation of citric acid. The name itaconic was devised as an anagram of aconitic. Itaconic acid is formed in the fermentation of some sugars. In 1929, Kinoshita first showed the acid as a metabolic product of Aspergillus itaconicus.

Source

Itaconic acid is formed by the cytosolic enzyme aconitate decarboxylase from cis-aconitic acid. Another biosynthetic pathway from pyruvate through citramalic acid, citraconic acid, and itartaric acid also results in itaconic acid.

Chemical Properties

white to light beige crystalline powder

Uses

The major uses for itaconic acid are in copolymerizations, resins, plasticizers, and as lube oil additives.

Uses

Itaconic acid is used in the preparation of acrylonitrile-butadiene-styrene and acrylate latexes. It is also used to prepare poly-itaconic acid, resins biofuel components and ionomer cements. It finds application in the textile, chemical and pharmaceutical industries. It is also used as an additive in fibers and ion exchange resins to increase abrasion, waterproofing, physical resistance, dying affinity and better duration. Further, it acts as a co-monomer used in the preparation of acrylic fibers and rubbers, reinforced glass fiber, artificial diamonds and lens. In addition to this, it acts as a binder and sizing agent in non-weaving fibers.

Definition

ChEBI: A dicarboxylic acid that is methacrylic acid in which one of the methyl hydrogens is substituted by a carboxylic acid group.

Definition

itaconic acid: A product of the fermentationof the flamentous fungusAspergillus niger. Itaconic acid is usedcommercially in the production ofadhesives and paints.

General Description

Itaconic acid, an unsaturated dicarbonic organic acid, is a metabolic product of Aspergillus itaconicus.

Flammability and Explosibility

Non flammable

Purification Methods

Crystallise itaconic acid from EtOH, EtOH/water or EtOH/*benzene. [Beilstein 2 IV 2228.]

498-24-8
79-41-4
498-23-7
594-61-6
97-65-4
Synthesis of Itaconic acid from Mesaconic acid
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View Lastest Price from Itaconic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Itaconic acid pictures 2026-07-13 Itaconic acid
97-65-4
0.99 RongNa Biotechnology Co.,Ltd
Itaconic acid pictures 2026-07-13 Itaconic acid
97-65-4
1KG 99.5% 5000mt/year Jinan Finer Chemical Co., Ltd
Itaconic acid pictures 2026-07-09 Itaconic acid
97-65-4
$1.00-50.00 1KG 99% Henan Fengda Chemical Co., Ltd
  • Itaconic acid pictures
  • Itaconic acid
    97-65-4
  • $1.00-50.00
  • 99%
  • Henan Fengda Chemical Co., Ltd
methylene-butanedioicaci methylene-succinicaci Succinic acid, methylene- 3-CARBOXY-3-BUTENOIC ACID ITACONIC ACID 2-PROPENE-1,2-DICARBOXYLIC ACID PROPYLENEDICARBOXYLIC ACID itaconic acide ITACONIC ACID, 99+% ITACONIC ACID CRYSTALLINE 99+% ItaconicAcidForSynthesis ItaconicAcid99%Min Itaconic Acid 99%Min, Cas 2-methylenebutanedioate 2-methylidenebutanedioic acid Itaconsure Methylenebutanedioic acid Prop-2-ene-1,2-dicarbonic acid ITACONIC ACID pure L-Valine,(S)-α-Aminoisovaleric acid, L-2-Amino-3-methylbutanoic acid Methylenesuccinic acid, extra pure Itaconic acid,Methylenesuccinic acid Itaconic acid, 99+% 1KG Itaconic acid, 99+% 250GR 1-Propene-2,3-dicarboxylic acid 2-Methylenebutanedioic acid Propylene-1,2-dicarboxylic acid Methylenesuccinic Acid 2-Propene-1,2-dicarboxylic Acid METHYLENESUCCINIC ACID FOR SYNTHESIS Itaconic acid, AR,>99.0%(T) Butanedioic acid, 2-methylene- ItaconicAcid> ITACONIC ACID (13C5, 99%) Itaconic acid AR 99% Itaconic acid for synthesis 500GM Itaconic Acid 99% For Synthesis Yikang acid Itaconic acid, 10 mM in DMSO Itaconic acid, 98% Itaconic acid Methylenesuccinic acid Methylenebutanedioic acid 2-methylidenebutanedioate Itaconic Acid (IA) Butanedioic acid, methylene- METHYLENESUCCINIC ACID 97-65-4 97-56-4 CH2CCO2HCH2COOH H2CCCOOHCH2COOH 97654 HO2CCH2CCH2CO2H Organic Building Blocks Building Blocks C1 to C5 Carboxylic Acids Carbonyl Compounds Building Blocks C1 to C5 Carbonyl Compounds Carboxylic Acids